Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation (Q27332133)

26 June 2017

Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation (English)

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26 June 2017

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15

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Stefan Wirtz

Stefan Wirtz

12

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Gionata Fiorino

Gionata Fiorino

8

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Cord Brakebusch

Cord Brakebusch

15

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Arif B. Ekici

11

Arif B Ekici

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10

Silvio Danese

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Markus F Neurath

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Raja Atreya

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Imke Atreya

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3

Claudia Günther

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5

Kerstin Amann

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Ulrike Billmeier

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9

Stefania Vetrano

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13

Veronika Thonn

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26 June 2017

Rocío López-Posadas

1

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26 June 2017

Christoph Becker

2

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Stefan Tenzer

4

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Martin Bergö

16

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Alastair J M Watson

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language of work or name

English

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publication date

11 January 2016

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Journal of Clinical Investigation

26 June 2017

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126

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2

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611-626

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describes a project that uses

26 June 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4731169/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

21 March 2017

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Intracellular localization of the P21rho proteins

21 March 2017

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 March 2017

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Stem cells, self-renewal, and differentiation in the intestinal epithelium

21 March 2017

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21 March 2017

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MEK/ERK regulates adherens junctions and migration through Rac1

21 March 2017

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Intestinal homeostasis and its breakdown in inflammatory bowel disease

21 March 2017

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Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms.

7 April 2017

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Confocal endomicroscopy identifies loss of local barrier function in the duodenum of patients with Crohn's disease and ulcerative colitis

28 September 2017

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Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene

28 September 2017

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Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomics

28 September 2017

1 reference

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Aryl hydrocarbon receptor and colitis

28 September 2017

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Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice

28 September 2017

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Difference in F-actin depolymerization induced by toxin B from the Clostridium difficile strain VPI 10463 and toxin B from the variant Clostridium difficile serotype F strain 1470.

28 September 2017

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Increased epithelial gaps in the small intestine are predictive of hospitalization and surgery in patients with inflammatory bowel disease

28 September 2017

1 reference

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Recent advances in protein prenyltransferases: substrate identification, regulation, and disease interventions

28 September 2017

1 reference

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TNF-α-induced intestinal epithelial cell shedding: implications for intestinal barrier function

28 September 2017

1 reference

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Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

28 September 2017

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Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease

28 September 2017

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

28 September 2017

1 reference

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The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding.

28 September 2017

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RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

28 September 2017

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P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium

28 September 2017

1 reference

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Integrin alpha8beta1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism

28 September 2017

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28 September 2017

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The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.

28 September 2017

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Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor

28 September 2017

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GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer

28 September 2017

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Matrix metalloproteinases in inflammatory bowel disease: boon or a bane?

28 September 2017

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Inhibition of Rho A activity causes pemphigus skin blistering

28 September 2017

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Hydrophobic modifications of Ras proteins by isoprenoid groups and fatty acids--More than just membrane anchoring

28 September 2017

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Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

28 September 2017

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Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

28 September 2017

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Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

28 September 2017

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Pregnane X receptor agonists enhance intestinal epithelial wound healing and repair of the intestinal barrier following the induction of experimental colitis

28 September 2017

1 reference

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Epithelial barrier function in vivo is sustained despite gaps in epithelial layers

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

Spontaneous in vitro IL-6 production in various intestinal segments in patients with inflammatory bowel disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

Morphogenesis of the primitive gut tube is generated by Rho/ROCK/myosin II-mediated endoderm rearrangements

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731169

Epithelial NEMO links innate immunity to chronic intestinal inflammation

27 November 2018

1 reference

12 December 2020

High resolution colonoscopy in live mice

1 reference

12 December 2020

Intestinal permeability and genetic determinants in patients, first-degree relatives, and controls in a high-incidence area of Crohn's disease in Southern Italy

1 reference

12 December 2020

Mechanisms of epithelial cell shedding in the Mammalian intestine and maintenance of barrier function

1 reference

12 December 2020

Tissue distribution of dextran sulfate sodium (DSS) in the acute phase of murine DSS-induced colitis

1 reference

12 December 2020

Tumour necrosis factor alpha in stool as a marker of intestinal inflammation

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12 December 2020

Production of experimental ulcerative colitis in hamsters by dextran sulfate sodium and changes in intestinal microflora

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12 December 2020

Identifiers

DOI

10.1172/JCI80997

1 reference

OpenCitations bibliographic resource ID

26 June 2017

4120052

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference