Intestinal mucosal barrier function in health and disease (Q29618086)

Europe PubMed Central

title

Intestinal mucosal barrier function in health and disease (English)

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30 April 2017

author name string

Turner JR

series ordinal

1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19855405

30 April 2017

language of work or name

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30 April 2017

publication date

November 2009

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Nature Reviews Immunology

30 April 2017

published in

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volume

9

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page(s)

799-809

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issue

11

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19855405

Permeability of the rat small intestinal epithelium along the villus-crypt axis: effects of glucose transport

30 April 2017

cites work

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Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

31 March 2020

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CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

31 March 2020

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Mucosal vaccines: the promise and the challenge

31 March 2020

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Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut.

31 March 2020

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Dendritic cells in intestinal immune regulation.

31 March 2020

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The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

31 March 2020

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Role of CFTR in airway disease.

31 March 2020

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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

31 March 2020

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Regulated alkali secretion acts in tandem with unstirred layers to regulate mouse gastric surface pH.

31 March 2020

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In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death

31 March 2020

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The density of small tight junction pores varies among cell types and is increased by expression of claudin-2.

31 March 2020

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Interferon-gamma selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores.

31 March 2020

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Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

31 March 2020

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Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo

31 March 2020

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Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

31 March 2020

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Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture

31 March 2020

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Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption

31 March 2020

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Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

31 March 2020

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Intestinal glucose transport using perfused rat jejunum in vivo: model analysis and derivation of corrected kinetic constants.

31 March 2020

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Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

31 March 2020

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Regulation of human jejunal transmucosal resistance and MLC phosphorylation by Na(+)-glucose cotransport

31 March 2020

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Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

31 March 2020

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Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

31 March 2020

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Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers

31 March 2020

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Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha.

31 March 2020

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Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation

31 March 2020

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Proinflammatory cytokines tumor necrosis factor-alpha and interferon-gamma alter tight junction structure and function in the rat parotid gland Par-C10 cell line

31 March 2020

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Synergistic effects of tumor necrosis factor-alpha and thrombin in increasing endothelial permeability

31 March 2020

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Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis.

31 March 2020

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Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

31 March 2020

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Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

31 March 2020

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Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo

31 March 2020

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A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

31 March 2020

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Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

31 March 2020

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Roles of Rho/ROCK and MLCK in TNF-α-induced changes in endothelial morphology and permeability

31 March 2020

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Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter

31 March 2020

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Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease

31 March 2020

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LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms.

31 March 2020

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Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability

31 March 2020

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Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation

31 March 2020

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Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase-dependent fashion.

31 March 2020

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Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats.

31 March 2020

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LPS-induced lung inflammation is linked to increased epithelial permeability: role of MLCK.

31 March 2020

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Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents.

31 March 2020

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ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton

31 March 2020

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AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function

31 March 2020

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Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane

31 March 2020

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Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis

31 March 2020

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Caveolae-mediated internalization of occludin and claudin-5 during CCL2-induced tight junction remodeling in brain endothelial cells

31 March 2020

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Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process

31 March 2020

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TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration

31 March 2020

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Complex phenotype of mice lacking occludin, a component of tight junction strands.

31 March 2020

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

31 March 2020

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Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

31 March 2020

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

31 March 2020

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Energy-dependent regulation of cell structure by AMP-activated protein kinase

31 March 2020

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Downregulation of claudin-2 expression in renal epithelial cells by metabolic acidosis

31 March 2020

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Claudin-4 augments alveolar epithelial barrier function and is induced in acute lung injury

31 March 2020

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Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

31 March 2020

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Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

31 March 2020

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Increased expression of interleukin 17 in inflammatory bowel disease

31 March 2020

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Claudins regulate the intestinal barrier in response to immune mediators

31 March 2020

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Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site

31 March 2020

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Structure-function studies of claudin extracellular domains by cysteine-scanning mutagenesis.

31 March 2020

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Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

31 March 2020

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Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

31 March 2020

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A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

31 March 2020

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Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora

31 March 2020

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The primary defect in experimental ileitis originates from a nonhematopoietic source

31 March 2020

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Intestinal permeability and the prediction of relapse in Crohn's disease

31 March 2020

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Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

31 March 2020

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Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis

31 March 2020

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Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone

31 March 2020

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Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

31 March 2020

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Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

31 March 2020

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Crohn's disease--a permeability disorder of the tight junction?

31 March 2020

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Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk

31 March 2020

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Presentation and long-term follow-up of refractory celiac disease: comparison of type I with type II.

31 March 2020

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Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins

31 March 2020

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Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

31 March 2020

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Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease

31 March 2020

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JAM-A regulates permeability and inflammation in the intestine in vivo

31 March 2020

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Deletion of JAM-A causes morphological defects in the corneal epithelium.

31 March 2020

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A transient breach in the epithelial barrier leads to regulatory T-cell generation and resistance to experimental colitis

31 March 2020

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Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning.

31 March 2020

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Microbial influences in inflammatory bowel diseases

31 March 2020

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The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease.

31 March 2020

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Barrier-protective function of intestinal epithelial Toll-like receptor 2

31 March 2020

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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

31 March 2020

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

31 March 2020

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

31 March 2020

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Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

31 March 2020

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NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction

31 March 2020

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Chronic stimulation of Nod2 mediates tolerance to bacterial products

31 March 2020

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Evidence for a genetic defect in oral tolerance induction in inflammatory bowel disease.

31 March 2020

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Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation

31 March 2020

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Decrease in net stool output in cholera during intestinal perfusion with glucose-containing solutions

31 March 2020

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Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

31 March 2020

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Intestinal permeability in long-term follow-up of patients with celiac disease on a gluten-free diet

31 March 2020

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IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction

31 March 2020

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Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

31 March 2020

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Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells

31 March 2020

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Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(-/-) mice.

31 March 2020

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Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice

31 March 2020

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Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins

31 March 2020

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Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function

31 March 2020

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Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease

31 March 2020

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12 December 2020

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

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12 December 2020

Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments

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12 December 2020

Modulation of tumor necrosis factor-induced increase in renal (LLC-PK1) transepithelial permeability

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12 December 2020

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients

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12 December 2020

Measurements of the jejunal unstirred layer in normal subjects and patients with celiac disease

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12 December 2020

Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

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12 December 2020

Intestinal permeability in children with Crohn's disease and coeliac disease

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12 December 2020

Gut ischemia and mesenteric synthesis of inflammatory cytokines after hemorrhagic or endotoxic shock

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12 December 2020

Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice

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12 December 2020

Effect of phosphorylation of myosin light chain by myosin light chain kinase and protein kinase C on conformational change and ATPase activities of human platelet myosin

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12 December 2020

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Identifiers

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67701

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19855405

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30 April 2017

Consolidated OpenCitations Corpus – April 2017