The Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidance (Q27334778)

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scientific article (publication date: 2012)

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English	The Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidance	scientific article (publication date: 2012)

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24 January 2020

The Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidance (English)

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24 January 2020

Caenorhabditis elegans

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24 January 2020

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24 January 2020

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24 January 2020

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Ahmed M Mohamed

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24 January 2020

Jeffrey R Boudreau

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23 February 2012

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24 January 2020

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24 January 2020

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24 January 2020

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24 January 2020

e1002513

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24 January 2020

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23 February 2012

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Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

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21 March 2017

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21 March 2017

Bidirectional Eph-ephrin signaling during axon guidance

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21 March 2017

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21 March 2017

The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans

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21 March 2017

Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1

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21 March 2017

Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cells

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Nck adaptor proteins control the organization of neuronal circuits important for walking

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The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

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7 April 2017

Eph receptor signalling casts a wide net on cell behaviour

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PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans

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The C. elegans nck-1 gene encodes two isoforms and is required for neuronal guidance

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29 September 2017

The Arp2/3 complex, UNC-115/abLIM, and UNC-34/Enabled regulate axon guidance and growth cone filopodia formation in Caenorhabditis elegans

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EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts

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Arp2/3 branched actin network mediates filopodia-like bundles formation in vitro.

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29 September 2017

The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance

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29 September 2017

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Genes necessary for directed axonal elongation or fasciculation in C. elegans

1 reference

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2 June 2018

Characterization of loss-of-function and gain-of-function Eph receptor tyrosine kinase signaling in C. elegans axon targeting and cell migration

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002513

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Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002513

21 January 2018

The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002513

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002513

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1 reference

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1 reference

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Arp2/3 is a negative regulator of growth cone translocation

1 reference

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1 reference

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A role for C. elegans Eph RTK signaling in PTEN regulation.

1 reference

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21 January 2018

Two verprolin homology domains increase the Arp2/3 complex-mediated actin polymerization activities of N-WASP and WAVE1 C-terminal regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding the role of the G-actin-binding domain of Ena/VASP in actin assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel Eph receptor-interacting IgSF protein provides C. elegans motoneurons with midline guidepost function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of fibroblast motility by Ena/VASP proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PGEN.1002513

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

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Europe PubMed Central

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24 January 2020

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