Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1 (Q28585388)

31 January 2017

title

Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1 (English)

1 reference

Non-catalytic region of tyrosine kinase adaptor protein 1

31 January 2017

main subject

1 reference

GOA release 2020-03-11

Ephrin type-A receptor 3

1 reference

GOA release 2020-03-11

1 reference

Tianjing Hu

1

1 reference

31 January 2017

Guanfang Shi

2

1 reference

31 January 2017

Louise Larose

3

1 reference

31 January 2017

Gonzalo M. Rivera

4

1 reference

31 January 2017

Bruce J. Mayer

5

1 reference

31 January 2017

Renping Zhou

6

1 reference

31 January 2017

language of work or name

English

0 references

publication date

14 July 2009

1 reference

31 January 2017

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31 January 2017

volume

48

1 reference

31 January 2017

issue

27

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31 January 2017

page(s)

6369–6378

1 reference

Nck adaptor proteins control the organization of neuronal circuits important for walking

31 January 2017

cites work

1 reference

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alpha2-Chimaerin is an essential EphA4 effector in the assembly of neuronal locomotor circuits

17 March 2017

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Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling

17 March 2017

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Ephrin signaling in vivo: look both ways

17 March 2017

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17 March 2017

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Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases

17 March 2017

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Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling

17 March 2017

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The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

17 March 2017

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Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation

17 March 2017

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Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling

17 March 2017

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The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function

17 March 2017

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Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity

17 March 2017

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

17 March 2017

1 reference

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EphB receptors interact with NMDA receptors and regulate excitatory synapse formation

17 March 2017

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Regulation of repulsion versus adhesion by different splice forms of an Eph receptor

17 March 2017

1 reference

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Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation

17 March 2017

1 reference

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Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

17 March 2017

1 reference

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Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses

17 March 2017

1 reference

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Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

17 March 2017

1 reference

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Inhibition of myosin light chain kinase by p21-activated kinase

17 March 2017

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The Eph family receptors and ligands

17 March 2017

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Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

17 March 2017

1 reference

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Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathways

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis

17 March 2017

1 reference

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Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors

17 March 2017

1 reference

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Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

17 March 2017

1 reference

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SH2 domains recognize specific phosphopeptide sequences

17 March 2017

1 reference

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The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

17 March 2017

1 reference

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Biology of the p21-activated kinases

7 April 2017

1 reference

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Eph-ephrin bidirectional signaling in physiology and disease

7 April 2017

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Eph receptor signalling casts a wide net on cell behaviour

7 April 2017

1 reference

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A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

New exchanges in eph-dependent growth cone dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Eph receptor tyrosine kinases in tumor and tumor microenvironment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Src family kinases are involved in EphA receptor-mediated retinal axon guidance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Inducible clustering of membrane-targeted SH3 domains of the adaptor protein Nck triggers localized actin polymerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

The Nck family of adapter proteins: regulators of actin cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

The SH2/SH3 adaptor protein dock interacts with the Ste20-like kinase misshapen in controlling growth cone motility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Dominant-negative mutants of the SH2/SH3 adapters Nck and Grb2 inhibit MAP kinase activation and mesoderm-specific gene induction by eFGF in Xenopus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Multiple effects of ephrin-A5 on cortical neurons are mediated by SRC family kinases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Ephrins stimulate neurite outgrowth during early cortical neurogenesis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Ephrins stimulate or inhibit neurite outgrowth and survival as a function of neuronal cell type

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

Ephrin-A5 exerts positive or inhibitory effects on distinct subsets of EphA4-positive motor neurons.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

EphB forward signaling controls directional branch extension and arborization required for dorsal-ventral retinotopic mapping

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750895

EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19505147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

31 January 2017

0 references

1 reference