Fos proto-oncogene, AP-1 transcription factor subunit (Q2745522)

http://www.ebi.ac.uk/interpro/protein/P01100

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

DNA-binding transcription factor activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

18 references

8 April 2019

Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Transcriptional synergy mediated by SAF-1 and AP-1: critical role of N-terminal polyalanine and two zinc finger domains of SAF-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Thermodynamic analysis of Jun-Fos coiled coil peptide antagonists

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Visualization of AP-1 NF-kappaB ternary complexes in living cells by using a BiFC-based FRET.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

The protein interaction landscape of the human CMGC kinase group

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

A comprehensive resource of interacting protein regions for refining human transcription factor networks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

A human MAP kinase interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

protein heterodimerization activity

IPI

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

double-stranded DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

8 April 2019

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

DNA-binding transcription factor activity

ISA

4 references

8 April 2019

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

endoplasmic reticulum

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

4 references

31 January 2017

Platelet-activating factor induction of activator protein-1 signaling in bronchial epithelial cells

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

31 January 2017

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

6 references

8 April 2019

Platelet-activating factor induction of activator protein-1 signaling in bronchial epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8(+) T suppressor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

transcription factor AP-1 complex

cellular response to extracellular stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to muscle stretch

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to immobilization stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

cellular response to calcium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

SMAD protein signal transduction

1 reference

8 April 2019

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to organic cyclic compound

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to light stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to progesterone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to corticosterone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to mechanical stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

positive regulation of osteoclast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

cellular response to reactive oxygen species

1 reference

31 January 2017

Reactive oxygen species mediates the apoptosis induced by transforming growth factor beta(2) in human lens epithelial cells

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

Fc-epsilon receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

positive regulation of transcription, DNA-templated

1 reference

31 January 2017

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100

1 reference

8 April 2019

Role of DNA 5-methylcytosine transferase in cell transformation by fos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

cellular response to hormone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

conditioned taste aversion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

skeletal muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

Platelet-activating factor induction of activator protein-1 signaling in bronchial epithelial cells

inflammatory response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

response to toxic substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

cytokine-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

cellular response to reactive oxygen species

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

4 references

8 April 2019

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

8 April 2019

Presenilin 1 suppresses the function of c-Jun homodimers via interaction with QM/Jif-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

cellular response to cadmium ion

1 reference

8 April 2019

Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100

Basic-leucine zipper domain

Gene Atlas image

PBB GE FOS 209189 at fs.png
732 × 530; 10 KB

0 references

has part(s)

1 reference

stated in

InterPro Release 71.0