Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide (Q27473483)

1

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Petra Augstein

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Antonis K Moustakas

3

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George K Papadopoulos

4

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Silvia Gregori

5

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Luciano Adorini

6

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David C Jackson

7

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Leonard C Harrison

Journal of Clinical Investigation

8

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language of work or name

English

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publication date

May 2003

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published in

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volume

111

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page(s)

1365-71

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issue

9

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cites work

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Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus

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27 November 2018

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27 November 2018

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Modelling of the MHC II allele I-A(g7) of NOD mouse: pH-dependent changes in specificity at pockets 9 and 6 explain several of the unique properties of this molecule

27 November 2018

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12 December 2020

Systemic Administration of Agonist Peptide Blocks the Progression of Spontaneous CD8-Mediated Autoimmune Diabetes in Transgenic Mice Without Bystander Damage

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12 December 2020

Mucosal Antigen Primes Diabetogenic Cytotoxic T-Lymphocytes Regardless of Dose or Delivery Route

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12 December 2020

Binding of longer peptides to the H-2Kb heterodimer is restricted to peptides extended at their C terminus: refinement of the inherent MHC class I peptide binding criteria

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12 December 2020

Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type 1 diabetes

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12 December 2020

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes

1 reference

12 December 2020

Orally administered myelin basic protein in neonates primes for immune responses and enhances experimental autoimmune encephalomyelitis in adult animals

1 reference

12 December 2020

Induction by chronic autoimmune arthritis in DBA/1 mice by oral administration of type II collagen and Escherichia coli lipopolysaccharide

1 reference

12 December 2020

RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice

1 reference

12 December 2020

Induction of Autoimmune Diabetes by Oral Administration of Autoantigen

1 reference

12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis

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12 December 2020