Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes. (Q36437564)

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English	Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes.	scientific article

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14 October 2019

Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes (English)

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14 October 2019

Michelle B French

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14 October 2019

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14 October 2019

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G Rudy

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14 October 2019

N Stone

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14 October 2019

L C Harrison

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14 October 2019

P G Colman

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14 October 2019

P McNair

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14 October 2019

V Brusic

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14 October 2019

M C Honeyman

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14 October 2019

B Tait

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1 September 1995

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14 October 2019

Molecular Medicine

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14 October 2019

1

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14 October 2019

625-633

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14 October 2019

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14 October 2019

https://scigraph.springernature.com/pub.10.1007/bf03401603

0 references

Prevention of autoimmune diabetes in non-obese diabetic mice by treatment with a class II major histocompatibility complex-blocking peptide

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30 September 2017

The immunologic insult in type 1 diabetes

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30 September 2017

Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease

1 reference

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30 September 2017

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Antigen mimicry in autoimmune disease sharing of amino acid residues critical for pathogenic T cell activation

1 reference

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30 September 2017

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Analysis of the human T-cell response to picornaviruses: identification of T-cell epitopes close to B-cell epitopes in poliovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Induction of autoreactive B cells allows priming of autoreactive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Islet-reactive T cells are a marker of preclinical insulin-dependent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Islet cell antigens in insulin-dependent diabetes: Pandora's box revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

30 September 2017

Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Increased proinsulin levels as an early indicator of B-cell dysfunction in non-diabetic twins of type 1 (insulin-dependent) diabetic patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Elevated proinsulin in healthy siblings of IDDM patients independent of HLA identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Proinsulin and C-peptide at onset and during 12 months cyclosporin treatment of type 1 (insulin-dependent) diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Proinsulin autoantibodies: association with type I diabetes but not with islet cell antibodies, insulin autoantibodies or HLA-DR type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Insulitis in type 1 (insulin-dependent) diabetes mellitus in man--macrophages, lymphocytes, and interferon-gamma containing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

H-2Kd-restricted antigenic peptides share a simple binding motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Elevated proinsulin levels related to islet cell antibodies in first-degree relatives of IDDM patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

28 June 2018

Proinsulin levels in newborn siblings of type 1 (insulin-dependent) diabetic children and their mothers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

21 September 2018

Antibodies to glutamic acid decarboxylase in at-risk and clinical insulin-dependent diabetic subjects: relationship to age, sex and islet cell antibody status, and temporal profile.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

21 September 2018

T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

21 September 2018

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229979

21 September 2018

On the appearance of islet associated autoimmunity in offspring of diabetic mothers: a prospective study from birth

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self peptides isolated from MHC glycoproteins of non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of IgG autoantibodies against human proinsulin in patients with IDDM before insulin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Examination of islets in the pancreas biopsy specimens from newly diagnosed Type 1 (insulin-dependent) diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivity to human islets and fetal pig proislets by peripheral blood mononuclear cells from subjects with preclinical and clinical insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of cyclophosphamide-induced and spontaneous diabetes in NOD/Shi/Kbe mice by anti-MHC class I Kd monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinsulin autoantibodies are more closely associated with type 1 (insulin-dependent) diabetes mellitus than insulin autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/8529129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03401603

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8529129%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8529129%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8529129%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

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