Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus (Q27486122)

11

0 references

Iris Antes

4

object named as

Iris Antes

0 references

author name string

Christoph Welsch

1

0 references

Francisco S Domingues

2

0 references

Simone Susser

3

0 references

Christoph Hartmann

5

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Gabriele Mayr

6

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Andreas Schlicker

7

0 references

Mario Albrecht

describes a project that uses

9

0 references

language of work or name

1 reference

23 January 2008

0 references

published in

Genome Biology

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volume

9

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issue

1

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page(s)

R16

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Cytoscape

object named as

Cytoscape

2 references

Europe PubMed Central

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha

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SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells

20 March 2017

1 reference

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The Universal Protein Resource (UniProt): an expanding universe of protein information

20 March 2017

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MUSCLE: multiple sequence alignment with high accuracy and high throughput

20 March 2017

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Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease

20 March 2017

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

20 March 2017

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Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes

20 March 2017

1 reference

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The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism

20 March 2017

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Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

20 March 2017

1 reference

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

20 March 2017

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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

20 March 2017

1 reference

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Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

20 March 2017

1 reference

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Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

20 March 2017

1 reference

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VMD: visual molecular dynamics

20 March 2017

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

20 March 2017

1 reference

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

20 March 2017

1 reference

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On the size of the active site in proteases. I. Papain

20 March 2017

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Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose

20 March 2017

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SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny

7 April 2017

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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

7 April 2017

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IRECS: a new algorithm for the selection of most probable ensembles of side-chain conformations in protein models

7 April 2017

1 reference

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Discovery and development of VX-950, a novel, covalent, and reversible inhibitor of hepatitis C virus NS3.4A serine protease

29 September 2017

1 reference

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Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations

29 September 2017

1 reference

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Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients.

29 September 2017

1 reference

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Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization

29 September 2017

1 reference

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Hepatitis C virus protease inhibitors: current progress and future challenges

29 September 2017

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Detailed analysis of scoring functions for virtual screening

29 September 2017

1 reference

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Solution structure and dynamics of the single-chain hepatitis C virus NS3 protease NS4A cofactor complex

29 September 2017

1 reference

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Positioning hydrogen atoms by optimizing hydrogen-bond networks in protein structures

29 September 2017

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Novel inhibitors of hepatitis C NS3-NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid

29 September 2017

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Computing topological parameters of biological networks.

2 June 2018

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Conformational analysis of alternative protein structures

27 November 2018

1 reference

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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir

27 November 2018

1 reference

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SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Viral kinetics in patients with chronic hepatitis C treated with the serine protease inhibitor BILN 2061.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Inhibitors of hepatitis C virus NS3·4A protease 1. Non-Charged tetrapeptide variants

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Effect of naturally occurring active site mutations on hepatitis C virus NS3 protease specificity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

A fast flexible docking method using an incremental construction algorithm.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395260

Do structurally similar ligands bind in a similar fashion?

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18215275

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/GB-2008-9-1-R16

1 reference

Dimensions Publication ID

1002359010

0 references

1 reference

1 reference

PubMed publication ID

18215275

1 reference