Effects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various Genotypes (Q27486248)

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2415805/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region

2 June 2018

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2 June 2018

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Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus

2 June 2018

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A steady-state and pre-steady-state kinetic analysis of the NTPase activity associated with the hepatitis C virus NS3 helicase domain

2 June 2018

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Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein

2 June 2018

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RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase

2 June 2018

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27 November 2018

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A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B.

27 November 2018

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Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis

27 November 2018

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Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy

27 November 2018

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Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.

27 November 2018

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Inhibition of the helicase activity of HCV NTPase/helicase by 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide-5 '-triphosphate (ribavirin-TP).

27 November 2018

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Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase

27 November 2018

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Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin

27 November 2018

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The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

27 November 2018

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Only a small fraction of purified hepatitis C RNA-dependent RNA polymerase is catalytically competent: implications for viral replication and in vitro assays

27 November 2018

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Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras

27 November 2018

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27 November 2018

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