The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo (Q27490490)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19674968%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo (English)

1 reference

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5 February 2020

0 references

1 reference

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3

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5 February 2020

Lars Frelin

5

1 reference

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5 February 2020

author name string

Malte Kriegs

1

1 reference

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5 February 2020

Michael Bruns

4

1 reference

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5 February 2020

Gustaf Ahlén

6

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5 February 2020

Matti Sällberg

7

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5 February 2020

Eberhard Hildt

8

1 reference

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5 February 2020

Tilmann Bürckstümmer

2

1 reference

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5 February 2020

language of work or name

English

0 references

publication date

12 August 2009

1 reference

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Journal of Biological Chemistry

5 February 2020

published in

1 reference

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5 February 2020

volume

284

1 reference

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5 February 2020

issue

41

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5 February 2020

page(s)

28343-28351

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Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms

5 February 2020

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Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication

20 March 2017

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Antiviral actions of interferons

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Characterization of cell lines carrying self-replicating hepatitis C virus RNAs

20 March 2017

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Antiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinase

20 March 2017

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NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

20 March 2017

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Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

20 March 2017

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Hepatitis C virus NS5A protein binds TBP and p53, inhibiting their DNA binding and p53 interactions with TBP and ERCC3

20 March 2017

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Course and outcome of hepatitis C

20 March 2017

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Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus

7 April 2017

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Viral hepatitis and liver cancer: the case of hepatitis C.

7 April 2017

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The interferon response circuit: induction and suppression by pathogenic viruses

29 September 2017

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Viruses know it all: new insights into IFN networks

29 September 2017

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Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain.

29 September 2017

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Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses

29 September 2017

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Hepatitis C virus NS5A: tales of a promiscuous protein

29 September 2017

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Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.

29 September 2017

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The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade

29 September 2017

1 reference

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Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways

29 September 2017

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The PreS2 activator MHBs(t) of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice

29 September 2017

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29 September 2017

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Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

29 September 2017

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29 September 2017

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29 September 2017

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The hepatitis B virus pre-S/S(t) transactivator is generated by 3' truncations within a defined region of the S gene

29 September 2017

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29 September 2017

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Low dose and gene gun immunization with a hepatitis C virus nonstructural (NS) 3 DNA-based vaccine containing NS4A inhibit NS3/4A-expressing tumors in vivo.

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2 June 2018

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2 June 2018

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2 June 2018

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Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growth

2 June 2018

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Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice

21 January 2018

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In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes

21 January 2018

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Lectin histochemistry of the lymphoid organs of the chicken

21 January 2018

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Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3/4A gene

21 January 2018

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Expression profiling on chronically rejected transplant kidneys.

21 January 2018

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Expression of hepatitis C virus non-structural 5A protein in the liver of transgenic mice

21 January 2018

1 reference

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Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.038877

Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.038877

Structural biology of hepatitis C virus

21 January 2018

1 reference

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Activation of c-Raf-1 kinase signal transduction pathway in alpha(7) integrin-deficient mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19674968

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.038877

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19674968%20AND%20SRC:MED&resulttype=core&format=json

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5 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c3mkgy6qjvewxncyecnq3uskkm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19674968%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

2 references