The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade (Q40601685)

21 September 2017

The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade (English)

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21 September 2017

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21 September 2017

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Andrew Macdonald

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author name string

Andrew Street

series ordinal

1

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PubMed ID

14709551

21 September 2017

Katherine Crowder

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3

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PubMed ID

14709551

21 September 2017

language of work or name

English

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publication date

5 January 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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13

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21 September 2017

12232-12241

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Differential regulation of cyclins D1 and D3 in hepatocyte proliferation.

21 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Replication of hepatitis C virus

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Protein modules and signalling networks

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

21 January 2018

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The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

The phosphoinositide 3-kinase pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Structural insight into substrate specificity and regulatory mechanisms of phosphoinositide 3-kinases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

21 January 2018

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Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling

21 January 2018

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HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

21 January 2018

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Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

21 January 2018

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Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.

21 January 2018

1 reference

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Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras

21 January 2018

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The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

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The inhibition of cAMP-dependent protein kinase by full-length hepatitis C virus NS3/4A complex is due to ATP hydrolysis

21 January 2018

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Identification of cellular proteins that bind to the human immunodeficiency virus type 1 nef gene product in vitro: a role for myristylation

21 January 2018

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

21 January 2018

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Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

21 January 2018

1 reference

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A novel peptide-SH3 interaction.

21 January 2018

1 reference

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SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

21 January 2018

1 reference

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An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312245200

Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Cell cycle regulation of hepatitis C virus internal ribosomal entry site-directed translation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Cell transformation by the middle T-antigen of polyoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312245200

Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312245200

Interaction between Nef and phosphatidylinositol-3-kinase leads to activation of p21-activated kinase and increased production of HIV

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312245200

Modular binding domains in signal transduction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312245200

21 January 2018

Identifiers

DOI

10.1074/JBC.M312245200

1 reference

21 September 2017

1 reference

PubMed ID

14709551