1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus (Q27490956)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071590%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus (English)

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16 January 2020

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8

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16 January 2020

3

Leen Vijgen

1 reference

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16 January 2020

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Pierre Raboisson

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16 January 2020

1

Origène Nyanguile

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16 January 2020

2

Benoit Devogelaere

1 reference

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16 January 2020

6

Maxwell D Cummings

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16 January 2020

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Oliver Lenz

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16 January 2020

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Katrien Vermeiren

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14

Pascale Dehertogh

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16 January 2020

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Sandrine Vendeville

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16 January 2020

19

Erna Cleiren

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16 January 2020

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Kenneth A Simmen

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16 January 2020

author name string

Walter Van den Broeck

4

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16 January 2020

Frederik Pauwels

5

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16 January 2020

Hendrik L De Bondt

7

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16 January 2020

Jan M Berke

9

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16 January 2020

Geneviève Vandercruyssen

11

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16 January 2020

Wendy Mostmans

13

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16 January 2020

Frédéric Delouvroy

15

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16 January 2020

Koen VanDyck

17

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16 January 2020

Koen Dockx

18

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16 January 2020

Gregory C Fanning

22

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16 January 2020

publication date

13 January 2010

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16 January 2020

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16 January 2020

volume

84

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16 January 2020

issue

6

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16 January 2020

page(s)

2923-2934

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Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase

16 January 2020

cites work

1 reference

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Structural basis for resistance of the genotype 2b hepatitis C virus NS5B polymerase to site A non-nucleoside inhibitors

20 March 2017

1 reference

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1,5-Benzodiazepine inhibitors of HCV NS5B polymerase

20 March 2017

1 reference

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Preclinical Characterization of PF-00868554, a Potent Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

20 March 2017

1 reference

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Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus

20 March 2017

1 reference

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1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors

20 March 2017

1 reference

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Development of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase Inhibitors

20 March 2017

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Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796

20 March 2017

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Activity of a Potent Hepatitis C Virus Polymerase Inhibitor in the Chimpanzee Model

20 March 2017

1 reference

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Binding-Site Identification and Genotypic Profiling of Hepatitis C Virus Polymerase Inhibitors

20 March 2017

1 reference

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Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

20 March 2017

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Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

20 March 2017

1 reference

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Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation

20 March 2017

1 reference

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Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

20 March 2017

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Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition

20 March 2017

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

20 March 2017

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Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase

20 March 2017

1 reference

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Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

20 March 2017

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Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

20 March 2017

1 reference

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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

20 March 2017

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20 March 2017

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

20 March 2017

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20 March 2017

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7 April 2017

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7 April 2017

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7 April 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors

29 September 2017

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29 September 2017

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A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations

29 September 2017

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Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site

2 June 2018

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Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients

2 June 2018

1 reference

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Mutation rate of the hepatitis C virus NS5B in patients undergoing treatment with ribavirin monotherapy

27 November 2018

1 reference

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Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors

27 November 2018

1 reference

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Analyzing a kinetic titration series using affinity biosensors

27 November 2018

1 reference

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Changing of hepatitis C virus genotype patterns in France at the beginning of the third millenium: The GEMHEP GenoCII Study.

27 November 2018

1 reference

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Arresting initiation of hepatitis C virus RNA synthesis using heterocyclic derivatives.

27 November 2018

1 reference

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27 November 2018

Identifiers

DOI

10.1128/JVI.01980-09

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071590%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071590%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

2 references