Lem3p YNL323W (Q27548949)

http://www.ebi.ac.uk/interpro/protein/P42838

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.27.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

ATPase-coupled intramembrane lipid transporter activity

2 references

21 June 2018

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

SGD

S000005267

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42838&geneProductId=UniProtKB:P42838

21 June 2018

Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae

SGD

S000005267

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42838&geneProductId=UniProtKB:P42838

protein binding

5 references

9 May 2019

Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter Drs2p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

An in vivo map of the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Mutational analysis of the Lem3p-Dnf1p putative phospholipid-translocating P-type ATPase reveals novel regulatory roles for Lem3p and a carboxyl-terminal region of Dnf1p independent of the phospholipid-translocating activity of Dnf1p in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Mapping functional interactions in a heterodimeric phospholipid pump

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

ATPase-coupled intramembrane lipid transporter activity

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

aminophospholipid flippase activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

1 reference

9 May 2019

plasma membrane

phospholipid-translocating ATPase complex

1 reference

9 May 2019

Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

endoplasmic reticulum

1 reference

21 June 2018

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

SGD

S000005267

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42838&geneProductId=UniProtKB:P42838

endoplasmic reticulum

Golgi apparatus

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

3 references

9 May 2019

9 May 2019

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

cytoplasm

HDA

1 reference

9 May 2019

Subcellular localization of the yeast proteome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

HDA

endoplasmic reticulum

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

9 May 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

cell surface receptor signaling pathway

HDA

biological process

1 reference

9 May 2019

A genetic analysis of glucocorticoid receptor signaling. Identification and characterization of ligand-effect modulators in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

regulation of vacuole organization

IGI

1 reference

9 May 2019

Opt2 mediates the exposure of phospholipids during cellular adaptation to altered lipid asymmetry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

phospholipid translocation

IGI

1 reference

9 May 2019

Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

aminophospholipid transport

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42838

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Transporter Classification Database ID

1 reference

20 March 2022

8.A.27.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database