Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine (Q27930460)

PubMed

12842877

1 December 2016

title

Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine (English)

1 reference

PubMed

Putative aminophospholipid translocase regulatory protein YNR048W

1 December 2016

0 references

1 reference

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

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Pamela K Hanson

1

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Lynn Malone

series ordinal

2

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Jennifer L Birchmore

series ordinal

3

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J Wylie Nichols

series ordinal

4

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language of work or name

English

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publication date

19 September 2003

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published in

1 reference

PubMed

12842877

The activities of four anticancer alkyllysophospholipids against Leishmania donovani, Trypanosoma cruzi and Trypanosoma brucei

1 December 2016

volume

278

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issue

38

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page(s)

36041-50

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cites work

1 reference

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The activity of alkyl phosphorylcholines and related derivatives against Leishmania donovani

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Hexadecylphosphocholine: oral treatment of visceral leishmaniasis in mice

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Trial of oral miltefosine for visceral leishmaniasis

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Miltefosine, an oral agent, for the treatment of Indian visceral leishmaniasis

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Treatment of American cutaneous leishmaniasis with miltefosine, an oral agent

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Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years

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Induction of apoptosis in human leukemic cells by the ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine. A possible basis for its selective action

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Ether--lipid (alkyl-phospholipid) metabolism and the mechanism of action of ether--lipid analogues in Leishmania

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Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B.

21 January 2018

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Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator

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Identification and purification of aminophospholipid flippases

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Lipid traffic: the ABC of transbilayer movement

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Protein-mediated inward translocation of phospholipids occurs in both the apical and basolateral plasma membrane domains of epithelial cells.

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Retrograde lipid traffic in yeast: identification of two distinct pathways for internalization of fluorescent-labeled phosphatidylcholine from the plasma membrane

21 January 2018

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NBD-labeled phosphatidylcholine and phosphatidylethanolamine are internalized by transbilayer transport across the yeast plasma membrane

21 January 2018

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Energy-dependent flip of fluorescence-labeled phospholipids is regulated by nutrient starvation and transcription factors, PDR1 and PDR3.

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Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport

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Plasma membrane translocation of fluorescent-labeled phosphatidylethanolamine is controlled by transcription regulators, PDR1 and PDR3

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PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs

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Analogs of alkyllysophospholipids: Chemistry, effects on the molecular level and their consequences for normal and malignant cells

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End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiae.

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Generation of Saccharomyces cerevisiae deletants and basic phenotypic analysis of eight novel genes from the left arm of chromosome XIV.

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Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

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Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae

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A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

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Mutations in cell division cycle genes CDC36 and CDC39 activate the Saccharomyces cerevisiae mating pheromone response pathway

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Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae

21 January 2018

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Proteolysis and sterol regulation

21 January 2018

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The Clementine bistatic radar experiment

21 January 2018

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An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system

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Characterization of NOT5 that encodes a new component of the Not protein complex

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305263200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

12842877

1 reference

Consolidated OpenCitations Corpus – April 2017