CCR4-NOT core DEDD family RNase subunit POP2 YNR052C (Q27550161)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

RNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

3'-5'-exoribonuclease activity

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

14 February 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

IGI

14 February 2019

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

nuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

protein binding

11 references

8 April 2019

Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

An in vivo map of the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Functional organization of the yeast proteome by systematic analysis of protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

PUF proteins bind Pop2p to regulate messenger RNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Insights into the structure of the CCR4-NOT complex by electron microscopy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

poly(A)-specific ribonuclease activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

3'-5'-exoribonuclease activity

1 reference

8 April 2019

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

poly(A)-specific ribonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

cell component

P-body

1 reference

16 July 2018

A role for Q/N-rich aggregation-prone regions in P-body localization.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39008&geneProductId=UniProtKB:P39008

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

CCR4-NOT core complex

1 reference

16 July 2018

The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39008&geneProductId=UniProtKB:P39008

CCR4-NOT complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

1 reference

8 April 2019

mating projection tip

HDA

1 reference

8 April 2019

Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

transcription, DNA-templated

HDA

biological process

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39008&geneProductId=UniProtKB:P39008

1 reference

16 July 2018

transcription elongation from RNA polymerase II promoter

1 reference

8 April 2019

Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

positive regulation of transcription elongation from RNA polymerase II promoter

1 reference

8 April 2019

The multifunctional Ccr4-Not complex directly promotes transcription elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39008&geneProductId=UniProtKB:P39008

1 reference

16 July 2018

nucleic acid phosphodiester bond hydrolysis

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

RNA phosphodiester bond hydrolysis, exonucleolytic

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

nuclear-transcribed mRNA poly(A) tail shortening

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

8 April 2019

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

negative regulation of translation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

exonucleolytic catabolism of deadenylated mRNA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39008

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference