Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex (Q27687142)

CCR4-NOT core subunit NOT3 YIL038C

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CCR4-NOT core subunit NOT5 YPR072W

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CCR4-NOT core subunit CDC36 YDL165W

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CCR4-NOT core subunit CDC39 YCR093W

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author

Henning Urlaub

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Elena Conti

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Bertrand Séraphin

6

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Varun Bhaskar

object named as

Varun Bhaskar

1

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Jerome Basquin

3

object named as

Jérôme Basquin

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Vladimir V Roudko

2

object named as

Vladimir Roudko

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author name string

Kundan Sharma

Nature Structural & Molecular Biology

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language of work or name

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November 2013

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published in

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volume

20

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issue

11

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page(s)

1281-8

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cites work

The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

1 reference

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

21 April 2017

1 reference

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin

21 April 2017

1 reference

Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin

21 April 2017

1 reference

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

21 April 2017

1 reference

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs

21 April 2017

1 reference

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT

21 April 2017

1 reference

PUF proteins bind Pop2p to regulate messenger RNAs

21 April 2017

1 reference

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs

21 April 2017

1 reference

Ccr4-Not complex: the control freak of eukaryotic cells

21 April 2017

1 reference

Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex

21 April 2017

1 reference

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits

21 April 2017

1 reference

Human Ccr4-Not complexes contain variable deadenylase subunits

21 April 2017

1 reference

NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain

21 April 2017

1 reference

C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex

21 April 2017

1 reference

Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction

21 April 2017

1 reference

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex

21 April 2017

1 reference

Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice

21 April 2017

1 reference

CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death

21 April 2017

1 reference

Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex

21 April 2017

1 reference

The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p

21 April 2017

1 reference

A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery

21 April 2017

1 reference

Dali server: conservation mapping in 3D

21 April 2017

1 reference

Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs

21 April 2017

1 reference

RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex

21 April 2017

1 reference

LSm proteins form heptameric rings that bind to RNA via repeating motifs

21 April 2017

1 reference

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

21 April 2017

1 reference

An in vivo map of the yeast protein interactome

21 April 2017

1 reference

The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

21 April 2017

1 reference

Integration, scaling, space-group assignment and post-refinement

21 April 2017

1 reference

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 April 2017

1 reference

The Buccaneer software for automated model building. 1. Tracing protein chains

21 April 2017

1 reference

Features and development of Coot

21 April 2017

1 reference

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

21 April 2017

1 reference

Clustal W and Clustal X version 2.0

21 April 2017

1 reference

OpenMS - an open-source software framework for mass spectrometry

21 April 2017

1 reference

Open mass spectrometry search algorithm

21 April 2017

1 reference

Comparison of ARM and HEAT protein repeats

21 April 2017

1 reference

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

21 April 2017

1 reference

RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes.

21 April 2017

1 reference

21 January 2018

The Ccr4--not complex

1 reference

Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation

21 January 2018

1 reference

The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

21 January 2018

1 reference

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

21 January 2018

1 reference

A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

21 January 2018

1 reference

The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

21 January 2018

1 reference

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

21 January 2018

1 reference

CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context

21 January 2018

1 reference

The Not3/5 subunit of the Ccr4-Not complex: a central regulator of gene expression that integrates signals between the cytoplasm and the nucleus in eukaryotic cells

21 January 2018

1 reference

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.

21 January 2018

1 reference

The Ccr4-not complex and yTAF1 (yTaf(II)130p/yTaf(II)145p) show physical and functional interactions

21 January 2018

1 reference

Specific roles for the Ccr4-Not complex subunits in expression of the genome

21 January 2018

1 reference

Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex

21 January 2018

1 reference

Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression.

21 January 2018

1 reference

Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse

21 January 2018

1 reference

STRAP: editor for STRuctural Alignments of Proteins

21 January 2018

1 reference

ProteoWizard: open source software for rapid proteomics tools development

21 January 2018

1 reference

OpenMS and TOPP: Open Source Software for LC-MS Data Analysis

21 January 2018

1 reference

Investigation of protein–RNA interactions by mass spectrometry—Techniques and applications

21 January 2018

1 reference

Characterization of NOT5 that encodes a new component of the Not protein complex

21 January 2018

1 reference

The essential function of Not1 lies within the Ccr4-Not complex

31 March 2020

1 reference

Interaction between Not1p, a component of the Ccr4-not complex, a global regulator of transcription, and Dhh1p, a putative RNA helicase

31 March 2020

1 reference

Characterization of Mutations in NOT2 Indicates that it Plays an Important Role in Maintaining the Integrity of the CCR4–NOT Complex

31 March 2020

1 reference

Absence of the mitochondrial AAA protease Yme1p restores F0-ATPase subunit accumulation in an oxa1 deletion mutant of Saccharomyces cerevisiae

31 March 2020

1 reference

Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24121231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24121231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The TATA-binding protein-associated factor yTafII19p functionally interacts with components of the global transcriptional regulator Ccr4-Not complex and physically interacts with the Not5 subunit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24121231