Structure of the small G protein Rap2 in a non-catalytic complex with GTP (Q27620631)

GOA release 2020-03-11

GTP binding

1 reference

Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

GOA release 2020-03-11

author name string

J Ménétrey

series ordinal

1

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J Cherfils

series ordinal

2

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language of work or name

English

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publication date

15 November 1999

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published in

Proteins

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volume

37

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issue

3

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page(s)

465-73

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cites work

1 reference

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Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

21 January 2018

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GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins

21 January 2018

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All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

21 January 2018

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21 January 2018

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21 January 2018

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Effects of the ras-related rap2 protein on cellular proliferation

21 January 2018

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Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product

21 January 2018

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Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

21 January 2018

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Identification of a specific effector of the small GTP-binding protein Rap2

21 January 2018

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

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A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

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Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

21 January 2018

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AMoRe: an automated package for molecular replacement

21 January 2018

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The CCP4 suite: programs for protein crystallography

21 January 2018

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Ras-catalyzed hydrolysis of GTP: a new perspective from model studies

21 January 2018

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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

21 January 2018

1 reference

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

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The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

21 January 2018

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Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

21 January 2018

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Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

21 January 2018

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Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

21 January 2018

1 reference

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Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

21 January 2018

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Ras/Rap effector specificity determined by charge reversal

21 January 2018

1 reference

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Use of caged nucleotides to characterize unstable intermediates by X-ray crystallography

21 January 2018

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Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

21 January 2018

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Structural basis of activation and GTP hydrolysis in Rab proteins

21 January 2018

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Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

21 January 2018

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Kinetic amplification of enzyme discrimination

21 January 2018

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Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase

21 January 2018

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Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

21 January 2018

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Structure of the human ADP-ribosylation factor 1 complexed with GDP

21 January 2018

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The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms

21 January 2018

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Crystal structure of RhoA-GDP and its functional implications

21 January 2018

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Structural Basis for Activation of ARF GTPase

21 January 2018

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Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis

21 January 2018

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Determination of interaction sites on the small G protein RhoA for phospholipase D

21 January 2018

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Rho proteins: targets for bacterial toxins

21 January 2018

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G-protein diseases furnish a model for the turn-on switch

21 January 2018

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The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

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The Eleventh Datta Lecture. The structural basis for substrate recognition and control by protein kinases

21 January 2018

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The atomic structure of protein-protein recognition sites

21 January 2018

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Role of glycine-82 as a pivot point during the transition from the inactive to the active form of the yeast Ras2 protein.

21 January 2018

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The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

21 January 2018

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Defining the functions of trans-SNARE pairs

21 January 2018

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