Structure and regulation of the CDK5-p25(nck5a) complex (Q27635171)

1

0 references

R Dhavan

2

0 references

J Peng

3

0 references

L B Areces

4

0 references

L H Tsai

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

5

0 references

language of work or name

English

0 references

publication date

September 2001

0 references

published in

Molecular Cell

0 references

volume

8

0 references

issue

3

0 references

page(s)

657-69

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

The crystal structure of cyclin A

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Crystal structure of a gamma-herpesvirus cyclin-cdk complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Identification and structure characterization of a Cdk inhibitory peptide derived from neuronal-specific Cdk5 activator

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

A model of the complex between cyclin-dependent kinase 5 and the activation domain of neuronal Cdk5 activator

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Crystal structure of cyclin-dependent kinase 2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

GenTHREADER: an efficient and reliable protein fold recognition method for genomic sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

A novel disruption of cortical development in p35(-/-) mice distinct from reeler.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Molecular cloning of a cyclin-like protein associated with cyclin-dependent kinase 3 (cdk 3) in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Cyclin E is expressed in neurons and forms complexes with cdk5

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Functions of Pho85 cyclin-dependent kinases in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

The cyclin box fold: protein recognition in cell-cycle and transcription control

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Identification of functional domains in the neuronal Cdk5 activator protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Reconstitution of neuronal Cdc2-like kinase from bacteria-expressed Cdk5 and an active fragment of the brain-specific activator. Kinase activation in the absence of Cdk5 phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Structural basis of cyclin-dependent kinase activation by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

SMART: a web-based tool for the study of genetically mobile domains

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Site-specific phosphorylation of Lys-Ser-Pro repeat peptides from neurofilament H by cyclin-dependent kinase 5: structural basis for substrate recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Identification of substrate binding site of cyclin-dependent kinase 5

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021

Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900343-4

7 January 2021