Structure and stability of the ankyrin domain of the Drosophila Notch receptor (Q27642408)

24 March 2024

4

Doug Barrick

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author name string

Mark E. Zweifel

1

1 reference

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24 March 2024

Daniel J. Leahy

2

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24 March 2024

Frederick M. Hughson

3

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24 March 2024

language of work or name

English

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National Center for Biotechnology Information

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full work available at URL

24 March 2024

publication date

November 2003

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https://europepmc.org/articles/pmc2366946?pdf=render

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Portable Document Format

online access status

open access

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https://europepmc.org/articles/PMC2366946

24 March 2024

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https://europepmc.org/articles/PMC2366946?pdf=render

24 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1110%2Fps.03279003

24 March 2024

1 reference

https://onlinelibrary.wiley.com/doi/pdf/10.1110/ps.03279003

24 March 2024

1 reference

Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1

24 March 2024

0 references

12

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issue

11

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page(s)

2622-32

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cites work

1 reference

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SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

20 March 2017

1 reference

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Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta

20 March 2017

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X-ray structural analysis of the yeast cell cycle regulator Swi6 reveals variations of the ankyrin fold and has implications for Swi6 function

20 March 2017

1 reference

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The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

20 March 2017

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Structure of an IkappaBalpha/NF-kappaB complex

20 March 2017

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Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

20 March 2017

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The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA

20 March 2017

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Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations

20 March 2017

1 reference

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Structure of the cyclin-dependent kinase inhibitor p19Ink4d

20 March 2017

1 reference

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Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors

20 March 2017

1 reference

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Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

20 March 2017

1 reference

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Raster3D: photorealistic molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

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Notch signaling: cell fate control and signal integration in development

20 March 2017

1 reference

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Automated MAD and MIR structure solution

20 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

ALSCRIPT: a tool to format multiple sequence alignments

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Shape complementarity at protein/protein interfaces

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

The interpretation of protein structures: Estimation of static accessibility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Presenilin is required for activity and nuclear access of Notch in Drosophila

20 March 2017

1 reference

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

20 March 2017

1 reference

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Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Signalling downstream of activated mammalian Notch

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Coupling of folding and binding for unstructured proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

The ankyrin repeat: a diversity of interactions on a common structural framework

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Determination and analysis of urea and guanidine hydrochloride denaturation curves

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Measuring the stability of partly folded proteins using TMAO.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Operator-bound GalR dimers close DNA loops by direct interaction: tetramerization and inducer binding.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Threading a database of protein cores

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Limits of cooperativity in a structurally modular protein: response of the Notch ankyrin domain to analogous alanine substitutions in each repeat

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Studies of the ankyrin repeats of the Drosophila melanogaster Notch receptor. 2. Solution stability and cooperativity of unfolding

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Studies of the ankyrin repeats of the Drosophila melanogaster Notch receptor. 1. Solution conformational and hydrodynamic properties

27 November 2018

1 reference

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Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366946

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.

27 November 2018

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

27 November 2018

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Purification and properties of Gal repressor:pL-galR fusion in pKC31 plasmid vector

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Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

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Negative effect of the transcriptional activator GAL4

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Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats

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The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, σ28

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1 reference