Crystal Structure of KPC-2:&#160; Insights into Carbapenemase Activity in Class A β-Lactamases † , ‡ (Q27644490)

4

object named as

Robert A Bonomo

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Christopher R Bethel

2

object named as

Christopher R Bethel

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author name string

Wei Ke

1

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Jodi M Thomson

Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase

3

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language of work or name

English

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publication date

15 May 2007

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published in

Biochemistry

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volume

46

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page(s)

5732-40

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issue

19

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cites work

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X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity

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Likelihood-enhanced fast translation functions

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Refinement of macromolecular structures by the maximum-likelihood method

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Detecting and overcoming crystal twinning

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7 April 2017

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29 September 2017

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Amino acid sequence requirements at residues 69 and 238 for the SME-1 beta-lactamase to confer resistance to beta-lactam antibiotics

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Emergence in Klebsiella pneumoniae of a chromosome-encoded SHV beta-lactamase that compromises the efficacy of imipenem

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27 November 2018

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12 December 2020

Role of Ser-237 in the substrate specificity of the carbapenem-hydrolyzing class A β-lactamase Sme-1

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12 December 2020

Mutagenesis of amino acid residues in the SHV-1 beta-lactamase: the premier role of Gly238Ser in penicillin and cephalosporin resistance

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Beta-lactamase stability of cefoxitin in comparison with other beta-lactam compounds

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12 December 2020

A disulfide bridge near the active site of carbapenem-hydrolyzing class A beta-lactamases might explain their unusual substrate profile

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12 December 2020