Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia (Q27649208)

5

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Martin A. Walsh

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object named as

Martin A Walsh

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author name string

Franca Rossi

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Valeria Montalbano

Journal of Biological Chemistry

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language of work or name

English

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publication date

8 February 2008

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published in

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volume

283

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issue

6

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page(s)

3559-66

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cites work

Endogenous neurotoxins from tryptophan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Unconventional ligands and modulators of nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Kynurenic acid leads, dopamine follows: a new case of volume transmission in the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Increased cortical kynurenate content in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Increased concentration of cerebral kynurenic acid alters stimulus processing and conditioned responding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Two kynurenine aminotransferases in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Biochemical and phenotypic abnormalities in kynurenine aminotransferase II-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Structure, evolution and action of vitamin B6-dependent enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Evolutionary relationships among pyridoxal-5'-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Evolutionary recruitment of biochemically specialized subdivisions of Family I within the protein superfamily of aminotransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

The manifold of vitamin B6 dependent enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Crystal structure of human kynurenine aminotransferase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Crystal structure of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3 at 2.20 A resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Crystal structures of Aedes aegypti kynurenine aminotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Integration of macromolecular diffraction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Substructure solution with SHELXD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Automated protein model building combined with iterative structure refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

From cofactor to enzymes. The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Modeling of the spatial structure of eukaryotic ornithine decarboxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Protein structure comparison by alignment of distance matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

Functional attributes of the phosphate group binding cup of pyridoxal phosphate-dependent enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707925200

21 January 2018

Identifiers

DOI

10.1074/JBC.M707925200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

18056996

1 reference

Consolidated OpenCitations Corpus – April 2017