Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡ (Q27651318)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18652489%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1 (English)

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11 January 2020

5

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11 January 2020

author name string

Judith Souphron

1

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11 January 2020

M Brett Waddell

2

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11 January 2020

Amir Paydar

3

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11 January 2020

Zeynep Tokgöz-Gromley

4

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11 January 2020

Brenda A Schulman

6

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11 January 2020

language of work or name

English

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publication date

25 July 2008

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11 January 2020

number of pages

9

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inferred from page(s)

published in

Biochemistry

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11 January 2020

volume

47

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11 January 2020

issue

34

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11 January 2020

page(s)

8961-8969

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Ribosomal proteins are targets for the NEDD8 pathway

11 January 2020

cites work

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Mutations in the Hydrophobic Core of Ubiquitin Differentially Affect Its Recognition by Receptor Proteins

20 March 2017

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20 March 2017

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Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.

20 March 2017

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Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

20 March 2017

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A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

20 March 2017

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20 March 2017

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The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

20 March 2017

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Conservation in the Mechanism of Nedd8 Activation by the Human AppBp1-Uba3 Heterodimer

20 March 2017

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Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

20 March 2017

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Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex

20 March 2017

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Structural basis for the specificity of ubiquitin C-terminal hydrolases

20 March 2017

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Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

20 March 2017

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Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

20 March 2017

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A new NEDD8-ligating system for cullin-4A

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

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A novel protein modification pathway related to the ubiquitin system

20 March 2017

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Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

20 March 2017

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Modification of proteins by ubiquitin and ubiquitin-like proteins

20 March 2017

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Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1

20 March 2017

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Polyubiquitin chains: polymeric protein signals

20 March 2017

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The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

20 March 2017

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20 March 2017

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7 April 2017

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A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

9 May 2017

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Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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2 June 2018

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27 November 2018

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Improving biosensor analysis

27 November 2018

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12 December 2020

Expression, purification, and characterization of the E1 for human NEDD8, the heterodimeric APPBP1-UBA3 complex

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12 December 2020

Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Site-directed mutagenesis of ubiquitin. Differential roles for arginine in the interaction with ubiquitin-activating enzyme

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12 December 2020

Identifiers

DOI

10.1021/BI800604C

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11 January 2020

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11 January 2020

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