X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation (Q27652789)

6

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Pierre-Jean Corringer

7

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Jean-Pierre Changeux

5

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Marc Baaden

3

object named as

Marc Baaden

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Hugues Nury

object named as

Hugues Nury

2

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Chantal Le Poupon

4

object named as

Chantal Le Poupon

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author name string

Nicolas Bocquet

Recent advances in Cys-loop receptor structure and function

1

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language of work or name

English

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publication date

1 January 2009

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published in

Nature

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volume

457

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issue

7225

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page(s)

111-4

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cites work

1 reference

Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels

21 April 2017

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X-ray structure of a prokaryotic pentameric ligand-gated ion channel

21 April 2017

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Structure and gating mechanism of the acetylcholine receptor pore

21 April 2017

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

21 April 2017

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

21 April 2017

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Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

21 April 2017

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Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

21 April 2017

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21 April 2017

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A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family

21 January 2018

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Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

21 January 2018

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A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor

21 January 2018

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Ligand-gated ion channels: mechanisms underlying ion selectivity

21 January 2018

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Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

21 January 2018

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Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

21 January 2018

1 reference

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The location of the gate in the acetylcholine receptor channel

21 January 2018

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Probing ion-channel pores one proton at a time

21 January 2018

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Control of cation permeation through the nicotinic receptor channel

21 January 2018

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Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker

21 January 2018

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Molecular tuning of fast gating in pentameric ligand-gated ion channels

21 January 2018

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Principal pathway coupling agonist binding to channel gating in nicotinic receptors

21 January 2018

1 reference

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Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

21 January 2018

1 reference

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Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

21 January 2018

1 reference

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Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

21 January 2018

1 reference

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21 January 2018

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12 December 2020

Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium

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12 December 2020

The influence of geometry, surface character, and flexibility on the permeation of ions and water through biological pores

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12 December 2020

Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: secondary structure implications

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12 December 2020

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

1 reference

12 December 2020