A competitive inhibitor traps LeuT in an open-to-out conformation (Q27653127)

22 June 2017

A competitive inhibitor traps LeuT in an open-to-out conformation (English)

1 reference

22 June 2017

4

0 references

Atsuko Yamashita

object named as

Atsuko Yamashita

3

1 reference

ORCID Public Data File 2021

author name string

Satinder K Singh

1

1 reference

22 June 2017

Chayne L Piscitelli

2

1 reference

22 June 2017

Eric Gouaux

4

1 reference

22 June 2017

language of work or name

English

0 references

publication date

1 December 2008

1 reference

22 June 2017

1 reference

22 June 2017

322

1 reference

22 June 2017

5908

1 reference

22 June 2017

1655-1661

1 reference

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

22 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

X-linked creatine-transporter gene (SLC6A8) defect: a new creatine-deficiency syndrome.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Transport mechanisms in acetylcholine and monoamine storage

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

The aqueous accessibility in the external half of transmembrane domain I of the GABA transporter GAT-1 Is modulated by its ligands

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Flux coupling in a neuronal glutamate transporter

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

20 March 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1166777

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Antidepressants targeting the serotonin reuptake transporter act via a competitive mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Mechanism for alternating access in neurotransmitter transporters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Substrate binding and formation of an occluded state in the leucine transporter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Structure and function of sodium-coupled GABA and glutamate transporters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Role of the GABA transporter in epilepsy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Neuronal and glial glycine transporters have different stoichiometries

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Neurotransmitter transporters in the central nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

The packing density in proteins: standard radii and volumes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

Mechanism of imipramine inhibition of platelet 5-hydroxytryptamine transport

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

The osmolyte strategy of normal human keratinocytes in maintaining cell homeostasis

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1166777

Neurotransmitter transporters as molecular targets for addictive drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1166777

The substrates of the gamma-aminobutyric acid transporter GAT-1 induce structural rearrangements around the interface of transmembrane domains 1 and 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1166777

Serotonin and cocaine-sensitive inactivation of human serotonin transporters by methanethiosulfonates targeted to transmembrane domain I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1166777

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832577

High-affinity uptake of [3H]norepinephrine by primary astrocyte cultures and its inhibition by tricyclic antidepressants

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19074341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19074341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1166777

1 reference

release_yxvq2xxmyjdphmvga7t2octtiq

22 June 2017

0 references

OpenCitations bibliographic resource ID

1073772

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference