Stabilization of the E* Form Turns Thrombin into an Anticoagulant (Q27655637)

2

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Zhiwei Chen

3

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Prafull S Gandhi

4

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Enrico Di Cera

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

24 July 2009

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published in

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volume

284

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issue

30

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page(s)

20034-40

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12 December 2020

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12 December 2020

The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo

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The Anticoagulant Thrombin Mutant W215A/E217A Has a Collapsed Primary Specificity Pocket

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12 December 2020

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12 December 2020

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12 December 2020

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Release of fibrinopeptides by the slow and fast forms of thrombin

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The role of the insertion loop around tryptophan 148 in tthe activity of thrombin

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Rational engineering of activity and specificity in a serine protease

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