Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4 (Q27646532)

2

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Leslie A Bush-Pelc

3

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F Scott Mathews

4

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Enrico Di Cera

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

10 July 2007

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published in

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volume

104

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issue

28

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page(s)

11603-8

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cites work

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Molecular mapping of thrombin-receptor interactions

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Binding of exosite ligands to human thrombin. Re-evaluation of allosteric linkage between thrombin exosites I and II

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Structural basis for thrombin activation of a protease-activated receptor: inhibition of intramolecular liganding

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The Anticoagulant Thrombin Mutant W215A/E217A Has a Collapsed Primary Specificity Pocket

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The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity

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Rapid kinetics of Na+ binding to thrombin

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Molecular recognition by thrombin. Role of the slow-->fast transition, site-specific ion binding energetics and thermodynamic mapping of structural components

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Kinetic pathway for the slow to fast transition of thrombin. Evidence of linked ligand binding at structurally distinct domains

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Allosteric effects of a monoclonal antibody against thrombin exosite II

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