Characterization of gene-activated human acid- -glucosidase: Crystal structure, glycan composition, and internalization into macrophages (Q27657379)

6

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Anthony H. Futerman

object named as

Anthony H Futerman

9

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author name string

Boris Brumshtein

1

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Paul Salinas

2

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Brian Peterson

3

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Victor Chan

4

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Philip J Savickas

7

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Gregory S Robinson

A plant-derived recombinant human glucocerebrosidase enzyme--a preclinical and phase I investigation

8

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publication date

January 2010

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published in

Glycobiology

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volume

20

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issue

1

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page(s)

24-32

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cites work

1 reference

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Acid beta-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy

20 March 2017

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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

20 March 2017

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The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis

20 March 2017

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X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease

20 March 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

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The mannose receptor family

20 March 2017

1 reference

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Structures and mechanisms of glycosyl hydrolases

20 March 2017

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Post-translational chemical modification(s) of proteins

20 March 2017

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The secretion and uptake of lysosomal phospholipase A2 by alveolar macrophages

20 March 2017

1 reference

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Effect of mannose chain length on targeting of glucocerebrosidase for enzyme replacement therapy of Gaucher disease

29 September 2017

1 reference

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1 alpha,25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production of the monokine, mononuclear cell factor

29 September 2017

1 reference

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Trafficking of lysosomal enzymes in normal and disease states

29 September 2017

1 reference

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Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.

29 September 2017

1 reference

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Identification of six new Gaucher disease mutations

29 September 2017

1 reference

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Secretion of TNF-alpha by alveolar macrophages in response to Candida albicans mannan

2 June 2018

1 reference

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Comparison of synthetic and natural glucosylceramides as substrate for glucosylceramidase assay

2 June 2018

1 reference

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Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

2 June 2018

1 reference

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Mannose-binding lectin augments the uptake of lipid A, Staphylococcus aureus, and Escherichia coli by Kupffer cells through increased cell surface expression of scavenger receptor A.

27 November 2018

1 reference

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X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease

27 November 2018

1 reference

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Rapid identification of mutations in the glucocerebrosidase gene of Gaucher disease patients by analysis of single-strand conformation polymorphisms

27 November 2018

1 reference

12 December 2020

A pharmacokinetic analysis of a novel enzyme replacement therapy with Gene-Activated human glucocerebrosidase (GA-GCB) in patients with type 1 Gaucher disease

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12 December 2020

Replacement therapy for inherited enzyme deficiency--macrophage-targeted glucocerebrosidase for Gaucher's disease

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Gaucher type 2 disease: identification of a novel transversion mutation in a French-Irish patient

1 reference

12 December 2020