Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V&#160;14i NKT Cells (Q27658388)

ChEBI release 2020-05-28

8

Steven A Porcelli

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Mitchell Kronenberg

10

Mitchell Kronenberg

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Dirk M Zajonc

9

Dirk M Zajonc

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Gerhard Wingender

3

Gerhard Wingender

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Moriya Tsuji

Moriya Tsuji

6

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Guy-Franck Richard

7

Richard W Franck

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author name string

Barbara A Sullivan

1

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Niranjana A Nagarajan

2

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Jing Wang

4

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Iain Scott

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

5

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language of work or name

English

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publication date

1 January 2010

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published in

Journal of Immunology

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volume

184

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page(s)

141-53

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issue

1

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cites work

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Innate Valpha14(+) natural killer T cells mature dendritic cells, leading to strong adaptive immunity

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CD1 mediated T cell recognition of glycolipids

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Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids

29 September 2017

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The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

29 September 2017

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On the road: progress in finding the unique pathway of invariant NKT cell differentiation

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Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice

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The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition

29 September 2017

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Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo

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Glycolipid antigen processing for presentation by CD1d molecules.

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

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CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution

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1 reference

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A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

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Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation.

27 November 2018

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A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner.

27 November 2018

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27 November 2018

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Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice

27 November 2018

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27 November 2018

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Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells

27 November 2018

1 reference

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Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids

27 November 2018

1 reference

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MHC class II-peptide complexes in dendritic cell lipid microdomains initiate the CD4 Th1 phenotype

27 November 2018

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TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

27 November 2018

1 reference

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The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex.

27 November 2018

1 reference

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A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

27 November 2018

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Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells

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12 December 2020

Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to Vα14 NKT cells

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Caveats in the design of MHC class I tetramer/antigen-specific T lymphocytes dissociation assays

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The C-Glycoside Analogue of the Immunostimulantα-Galactosylceramide (KRN7000): Synthesis and Striking Enhancement of Activity

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Processing of X-ray diffraction data collected in oscillation mode

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