The Prp19 WD40 Domain Contains a Conserved Protein Interaction Region Essential for Its Function (Q27661523)

GOA release 2020-03-11

Cwc2p YDL209C

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GOA release 2020-03-11

Kathleen L Gould

5

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author name string

Craig W Vander Kooi

1

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Liping Ren

2

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Ping Xu

3

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Melanie D Ohi

4

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Walter J Chazin

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing

6

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publication date

12 May 2010

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published in

Structure

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volume

18

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issue

5

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page(s)

584-93

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cites work

1 reference

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Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

20 March 2017

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Structural insights into the U-box, a domain associated with multi-ubiquitination

20 March 2017

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Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin

20 March 2017

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Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker

20 March 2017

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Optimal description of a protein structure in terms of multiple groups undergoing TLS motion

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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SOLVE and RESOLVE: automated structure solution and density modification

20 March 2017

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SOLVE and RESOLVE: automated structure solution, density modification and model building

20 March 2017

1 reference

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Mechanisms underlying ubiquitination

20 March 2017

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Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

20 March 2017

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MOLMOL: a program for display and analysis of macromolecular structures

20 March 2017

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The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing

20 March 2017

1 reference

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Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation

20 March 2017

1 reference

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The Prp19p-associated complex in spliceosome activation

20 March 2017

1 reference

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Characterization of interactions among the Cef1p-Prp19p-associated splicing complex

20 March 2017

1 reference

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Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.

20 March 2017

1 reference

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Functional association of essential splicing factor(s) with PRP19 in a protein complex

20 March 2017

1 reference

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Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast

20 March 2017

1 reference

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A new gun in town: the U box is a ubiquitin ligase domain

20 March 2017

1 reference

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20 March 2017

RING for destruction?

1 reference

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U-box proteins as a new family of ubiquitin ligases

20 March 2017

1 reference

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Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

20 March 2017

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Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer

7 April 2017

1 reference

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A role for ubiquitin in the spliceosome assembly pathway

29 September 2017

1 reference

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Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p

29 September 2017

1 reference

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Structural and functional analysis of essential pre-mRNA splicing factor Prp19p

29 September 2017

1 reference

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The structure of Ski8p, a protein regulating mRNA degradation: Implications for WD protein structure

29 September 2017

1 reference

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Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function

29 September 2017

1 reference

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The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases

29 September 2017

1 reference

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The Prp19-associated complex is required for specifying interactions of U5 and U6 with pre-mRNA during spliceosome activation

2 June 2018

1 reference

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The U box is a modified RING finger — a common domain in ubiquitination

27 November 2018

1 reference

12 December 2020

Modifications target spliceosome dynamics

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

A New Gun in Town: The U Box Is a Ubiquitin Ligase Domain

1 reference

12 December 2020