Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Disease (Q27663878)

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English	Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Disease	scientific article

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scholarly article

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Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Disease (English)

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prion protein family

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3

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David Eisenberg

4

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author name string

Marcin I Apostol

1

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Michael R Sawaya

2

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language of work or name

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publication date

24 September 2010

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Journal of Biological Chemistry

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285

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39

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29671-5

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Conformational diversity in prion protein variants influences intermolecular beta-sheet formation

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Molecular basis for insulin fibril assembly

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Molecular mechanisms for protein-encoded inheritance

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Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

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20 March 2017

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

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20 March 2017

Structure of the cross-beta spine of amyloid-like fibrils

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20 March 2017

Updated projections of future vCJD deaths in the UK

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20 March 2017

NMR structure of the mouse prion protein domain PrP(121-231)

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20 March 2017

Phasercrystallographic software

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20 March 2017

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20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

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20 March 2017

The CCP4 suite: programs for protein crystallography

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20 March 2017

A general model of prion strains and their pathogenicity

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20 March 2017

[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae

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20 March 2017

Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms

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7 April 2017

Identifying the amylome, proteins capable of forming amyloid-like fibrils

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29 September 2017

Natural and synthetic prion structure from X-ray fiber diffraction

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29 September 2017

Kuru in the 21st century--an acquired human prion disease with very long incubation periods

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943325

29 September 2017

Prion disease genetics

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943325

29 September 2017

Contaminant effects on protein crystal morphology in different growth environments

1 reference

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29 September 2017

Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics

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29 September 2017

Nucleated conformational conversion and the replication of conformational information by a prion determinant

1 reference

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29 September 2017

Prion protein NMR structure and familial human spongiform encephalopathies

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29 September 2017

Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943325

29 September 2017

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

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29 September 2017

Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

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29 September 2017

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

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29 September 2017

Self-replication and scrapie

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29 September 2017

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

1 reference

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29 September 2017

Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB

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2 June 2018

The crystal structure of the globular domain of sheep prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Scrapie prions aggregate to form amyloid-like birefringent rods

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

X-ray diffraction of scrapie prion rods and PrP peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

The physical basis of how prion conformations determine strain phenotypes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Protein-only transmission of three yeast prion strains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Silent prions lying in wait: a two-hit model of prion/amyloid formation and infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Polymorphism at residue 129 modulates the conformational conversion of the D178N variant of human prion protein 90-231.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Role of N-terminal familial mutations in prion protein fibrillization and prion amyloid propagation in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Biochemical and structural studies of the prion protein polymorphism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

A new PRNP mutation (G131V) associated with Gerstmann-Sträussler-Scheinker disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.158303

21 January 2018

Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20685658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of codon 129 genotype in human growth hormone-treated CJD patients in France and the UK

1 reference

https://pubmed.ncbi.nlm.nih.gov/20685658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20685658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HOLLOW: generating accurate representations of channel and interior surfaces in molecular structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/20685658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variant CJD in an individual heterozygous for PRNP codon 129

1 reference

https://pubmed.ncbi.nlm.nih.gov/20685658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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