Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin) (Q27650849)

4

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David Eisenberg

7

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Michael R Sawaya

object named as

Michael R Sawaya

3

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author name string

Jed J W Wiltzius

1

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Stuart A Sievers

2

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Dmitriy Popov

5

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Christian Riekel

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

6

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publication date

September 2008

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published in

Protein Science

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volume

17

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issue

9

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page(s)

1467-74

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cites work

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Structure of the cross-beta spine of amyloid-like fibrils

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Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone

20 March 2017

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Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

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Membrane interaction of islet amyloid polypeptide

29 September 2017

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Polymorphism in the intermediates and products of amyloid assembly

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The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

29 September 2017

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Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis

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Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid

29 September 2017

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Amylin agonists: a novel approach in the treatment of diabetes

29 September 2017

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Progress towards a molecular-level structural understanding of amyloid fibrils

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Full-length rat amylin forms fibrils following substitution of single residues from human amylin

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Role of islet amyloid in type 2 diabetes mellitus: consequence or cause?

29 September 2017

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Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

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A possible role for pi-stacking in the self-assembly of amyloid fibrils

29 September 2017

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Islet amyloid and type 2 diabetes mellitus

29 September 2017

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Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

29 September 2017

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Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide

29 September 2017

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Amylin compared with calcitonin gene-related peptide: structure, biology, and relevance to metabolic disease

29 September 2017

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Structural characterisation of islet amyloid polypeptide fibrils

29 September 2017

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Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

2 June 2018

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The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin

27 November 2018

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Role of aromatic interactions in amyloid formation by peptides derived from human Amylin

27 November 2018

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Identifying structural features of fibrillar islet amyloid polypeptide using site-directed spin labeling

27 November 2018

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Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation

27 November 2018

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The mechanism of insulin action on islet amyloid polypeptide fiber formation

27 November 2018

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Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation

27 November 2018

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Islet amyloid polypeptide: identification of long-range contacts and local order on the fibrillogenesis pathway

27 November 2018

1 reference

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Effects of sequential proline substitutions on amyloid formation by human amylin20-29.

27 November 2018

1 reference

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Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM).

27 November 2018

1 reference

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Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the severity of islet amyloidosis

27 November 2018

1 reference

12 December 2020

Amyloid Fibril Formation from Full-Length and Fragments of Amylin

1 reference

12 December 2020

X-ray diffraction studies on amyloid filaments

1 reference

12 December 2020

Polymorphic Fibrillar Assembly of Human Amylin

1 reference

12 December 2020

Identifiers

DOI

10.1110/PS.036509.108

1 reference

3621958

3621958

1 reference

1 reference

1 reference