Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters (Q27663981)

5

object named as

Irene T Weber

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author name string

Chen-Hsiang Shen

1

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Yuan-Fang Wang

2

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Robert W Harrison

Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

4

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language of work or name

English

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publication date

September 2010

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published in

FEBS Journal

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volume

277

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issue

18

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page(s)

3699-714

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cites work

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Probing the S1/S1' substrate binding pocket geometry of HIV-1 protease with modified aspartic acid analogues

29 September 2017

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Hydrophobic sliding: a possible mechanism for drug resistance in human immunodeficiency virus type 1 protease

29 September 2017

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2 June 2018

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The 80's loop (residues 78 to 85) is important for the differential activity of retroviral proteases.

2 June 2018

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HIV protease mutations associated with amprenavir resistance during salvage therapy: importance of I54M.

21 January 2018

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Covariation of amino acid positions in HIV-1 protease

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Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir-binding site

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Energy calculations and analysis of HIV-1 protease-inhibitor crystal structures

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High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains

21 January 2018

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Influence of flanking sequences on the dimer stability of human immunodeficiency virus type 1 protease

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3

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Contribution of hydrophobic interactions to protein stability

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12 December 2020

Characterization of two hydrophobic methyl clusters in HIV-1 protease by NMR spin relaxation in solution

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Mechanism of drug resistance revealed by the crystal structure of the unliganded HIV-1 protease with F53L mutation

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Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: theory and practice

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12 December 2020