Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged (Q27664038)

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English	Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged	scientific article

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9 February 2020

Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged (English)

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9 February 2020

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9 February 2020

Dennis R. Burton

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object named as

Dennis R Burton

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9 February 2020

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Zara Fulton

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9 February 2020

Ian A Wilson

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11 August 2010

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9 February 2020

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10

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Journal of Virology

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9 February 2020

10690-10699

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9 February 2020

Molecular architecture of native HIV-1 gp120 trimers

1 reference

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20 March 2017

Structural definition of a conserved neutralization epitope on HIV-1 gp120

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20 March 2017

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

1 reference

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20 March 2017

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20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

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20 March 2017

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20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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20 March 2017

Main-chain bond lengths and bond angles in protein structures

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20 March 2017

The antigenic structure of the HIV gp120 envelope glycoprotein

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20 March 2017

Structural basis of lectin-carbohydrate recognition

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20 March 2017

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

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7 April 2017

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

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7 April 2017

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7 April 2017

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

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7 April 2017

Very few substitutions in a germ line antibody are required to initiate significant domain exchange.

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29 September 2017

Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds

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29 September 2017

Challenges for structure-based HIV vaccine design

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29 September 2017

Specificities of broadly neutralizing anti-HIV-1 sera

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29 September 2017

Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strains

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29 September 2017

Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

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29 September 2017

A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.

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29 September 2017

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

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29 September 2017

An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies

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29 September 2017

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120

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Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

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29 September 2017

Novel template-assembled oligosaccharide clusters as epitope mimics for HIV-neutralizing antibody 2G12. Design, synthesis, and antibody binding study

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29 September 2017

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29 September 2017

Binding of high-mannose-type oligosaccharides and synthetic oligomannose clusters to human antibody 2G12: implications for HIV-1 vaccine design

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29 September 2017

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans

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Toward a carbohydrate-based HIV-1 vaccine: synthesis and immunological studies of oligomannose-containing glycoconjugates.

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Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility

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Fully Synthetic Carbohydrate HIV Antigens Designed on the Logic of the 2G12 Antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702629

12 December 2020

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inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/20702629

12 December 2020

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Antigen drives very low affinity B cells to become plasmacytes and enter germinal centers

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12 December 2020

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10.1128/JVI.01110-10

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Consolidated OpenCitations Corpus – April 2017

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