A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex (Q27664209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20801130%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex (English)

1 reference

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13 February 2020

1

1 reference

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13 February 2020

Yin-Biao Sun

series ordinal

2

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13 February 2020

author name string

Monica X Li

series ordinal

3

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13 February 2020

Brian D Sykes

series ordinal

4

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13 February 2020

language of work or name

English

0 references

publication date

27 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20801130%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular and Cellular Cardiology

13 February 2020

published in

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13 February 2020

volume

49

1 reference

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13 February 2020

issue

6

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13 February 2020

page(s)

1031-1041

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Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: The basis of W7 as an inhibitor of cardiac muscle contraction

13 February 2020

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20 March 2017

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20 March 2017

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Bepridil opens the regulatory N-terminal lobe of cardiac troponin C

20 March 2017

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Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C

20 March 2017

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Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy

20 March 2017

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Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex

20 March 2017

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20 March 2017

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Structural based insights into the role of troponin in cardiac muscle pathophysiology

20 March 2017

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The effects of levosimendan and OR-1896 on isolated hearts, myocyte-sized preparations and phosphodiesterase enzymes of the guinea pig

20 March 2017

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20 March 2017

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7 April 2017

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Interaction of cardiac troponin with cardiotonic drugs: a structural perspective.

29 September 2017

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29 September 2017

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Mechanisms and use of calcium-sensitizing agents in the failing heart

29 September 2017

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29 September 2017

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The contractile apparatus as a target for drugs against heart failure: interaction of levosimendan, a calcium sensitiser, with cardiac troponin c.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Binding of a new Ca2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study.

29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Energetics of the induced structural change in a Ca2+ regulatory protein: Ca2+ and troponin I peptide binding to the E41A mutant of the N-domain of skeletal troponin C.

27 November 2018

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27 November 2018

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27 November 2018

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7 January 2021

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Isotope-filtered 2D NMR of a protein-peptide complex: study of a skeletal muscle myosin light chain kinase fragment bound to calmodulin

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Identification of binding sites for bepridil and trifluoperazine on cardiac troponin C

7 January 2021

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20801130

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NMR studies delineating spatial relationships within the cardiac troponin I-troponin C complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20801130

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.YJMCC.2010.08.019

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20801130%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20801130%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20801130

2 references