Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors (Q27667580)

1

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Noriko Simorowski

2

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Stephen F Traynelis

3

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Hiro Furukawa

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

4

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language of work or name

English

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publication date

2011

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published in

Nature Communications

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volume

2

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page(s)

294

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cites work

1 reference

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Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit

20 March 2017

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Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors

20 March 2017

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Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core

20 March 2017

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Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

20 March 2017

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

20 March 2017

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20 March 2017

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Glutamate receptor ion channels: structure, regulation, and function

22 April 2017

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Mechanism of positive allosteric modulators acting on AMPA receptors

20 March 2017

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Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists

20 March 2017

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Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

20 March 2017

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Control of assembly and function of glutamate receptors by the amino-terminal domain.

20 March 2017

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Stationary gating of GluN1/GluN2B receptors in intact membrane patches

29 September 2017

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Control of NMDA receptor function by the NR2 subunit amino-terminal domain

29 September 2017

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Postsynaptic response to stimulation of the Schaffer collaterals with properties similar to those of synaptosomal aspartate release

29 September 2017

1 reference

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Kinetic basis of partial agonism at NMDA receptors

29 September 2017

1 reference

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Mechanism of differential control of NMDA receptor activity by NR2 subunits

29 September 2017

1 reference

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Distinct gating modes determine the biphasic relaxation of NMDA receptor currents

29 September 2017

1 reference

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Activation of recombinant NR1/NR2C NMDA receptors

29 September 2017

1 reference

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Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds

29 September 2017

1 reference

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Reduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: evidence for an exocytotic mechanism

29 September 2017

1 reference

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Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate.

29 September 2017

1 reference

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The relationship between agonist potency and AMPA receptor kinetics

29 September 2017

1 reference

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Glutamate receptors at atomic resolution

29 September 2017

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Agonist-activated ion channels

29 September 2017

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Subunit arrangement and function in NMDA receptors

29 September 2017

1 reference

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Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors

29 September 2017

1 reference

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Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog.

29 September 2017

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Mechanism of partial agonist action at the NR1 subunit of NMDA receptors

29 September 2017

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Glutamate receptor gating.

29 September 2017

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Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles.

29 September 2017

1 reference

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Role of distinct NMDA receptor subtypes at central synapses

29 September 2017

1 reference

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Characterization of L-homocysteate-induced currents in Purkinje cells from wild-type and NMDA receptor knockout mice

29 September 2017

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Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors

29 September 2017

1 reference

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Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors

29 September 2017

1 reference

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Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat.

29 September 2017

1 reference

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Mechanisms of activation of glutamate receptors and the time course of excitatory synaptic currents.

29 September 2017

1 reference

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29 September 2017

1 reference

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Release of glutamate, aspartate, and gamma-aminobutyric acid from isolated nerve terminals

29 September 2017

1 reference

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Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

29 September 2017

1 reference

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An analysis of the action of a false transmitter at the neuromuscular junction

29 September 2017

1 reference

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Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits

29 September 2017

1 reference

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Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit.

2 June 2018

1 reference

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Slow excitatory postsynaptic currents mediated by N-methyl-D-aspartate receptors on cultured mouse central neurones

2 June 2018

1 reference

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L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor

2 June 2018

1 reference

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In vitro release and electrophysiological effects in situ of homocysteic acid, an endogenous N-methyl-(D)-aspartic acid agonist, in the mammalian striatum.

2 June 2018

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Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302728

NMDA channel behavior depends on agonist affinity

2 June 2018

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Mechanosensitive channels: multiplicity of families and gating paradigms.

2 June 2018

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Identification of a native low-conductance NMDA channel with reduced sensitivity to Mg2+ in rat central neurones

21 January 2018

1 reference

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Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1295

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

21 January 2018

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Assessing the distribution of parameters in models of ligand-receptor interaction: to log or not to log.

21 January 2018

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Mechanisms of Activation of Glutamate Receptors and the Time Course of Excitatory Synaptic Currents

21 January 2018

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Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus.

21 January 2018

1 reference

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Release of neuroactive substances: homocysteic acid as an endogenous agonist of the NMDA receptor

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21522138

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A false transmitter at excitatory synapses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21522138

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS1295

1 reference

Dimensions Publication ID

ADS bibcode

2011NatCo...2..294V

0 references

1046205300

0 references

1 reference

1 reference

PubMed publication ID

21522138

1 reference