Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1 (Q27671779)

19 October 2023

Jacqueline M Matthews

object named as

Jacqueline M Matthews

8

Jacqueline M

Matthews

1 reference

19 October 2023

Joel P Mackay

7

Joel P

Mackay

1 reference

19 October 2023

Merlin Crossley

6

Merlin

Crossley

1 reference

19 October 2023

author name string

Lorna Wilkinson-White

1

Lorna

Wilkinson-White

1 reference

19 October 2023

Siavoush Dastmalchi

3

Siavoush

Dastmalchi

1 reference

19 October 2023

Beeke Wienert

4

Beeke

Wienert

1 reference

19 October 2023

Philippa H Stokes

5

Philippa H

Stokes

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

0 references

publication date

30 August 2011

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published in

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volume

108

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issue

35

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page(s)

14443-8

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cites work

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Crystal Structures of Multiple GATA Zinc Fingers Bound to DNA Reveal New Insights into DNA Recognition and Self-Association by GATA

20 March 2017

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GATA-1 forms distinct activating and repressive complexes in erythroid cells

20 March 2017

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Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction

20 March 2017

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Characterization of the conserved interaction between GATA and FOG family proteins

20 March 2017

1 reference

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Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions

20 March 2017

1 reference

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Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

20 March 2017

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Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

20 March 2017

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The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG

20 March 2017

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The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation

20 March 2017

1 reference

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Chip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in Drosophila

20 March 2017

1 reference

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The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

20 March 2017

1 reference

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A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction

20 March 2017

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NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1

20 March 2017

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HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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20 March 2017

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MOLMOL: a program for display and analysis of macromolecular structures

22 April 2017

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

20 March 2017

1 reference

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Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis

20 March 2017

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Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy

20 March 2017

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Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

20 March 2017

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FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

20 March 2017

1 reference

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SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

20 March 2017

1 reference

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HADDOCK versus HADDOCK: new features and performance of HADDOCK2.0 on the CAPRI targets

20 March 2017

1 reference

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The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation

7 April 2017

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Human phenotypes associated with GATA-1 mutations

29 September 2017

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A positive role for NLI/Ldb1 in long-range beta-globin locus control region function

29 September 2017

1 reference

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Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins

29 September 2017

1 reference

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Information-driven protein-DNA docking using HADDOCK: it is a matter of flexibility

29 September 2017

1 reference

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Transcriptional control of fetal liver hematopoiesis: dominant negative effect of the overexpression of the LIM domain mutants of LMO2.

29 September 2017

1 reference

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Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167507

The N-terminal zinc finger of the erythroid transcription factor GATA-1 binds GATC motifs in DNA.

29 September 2017

1 reference

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A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167507

Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167507

Structure and function of LIM domains

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167507

Identification of the key LMO2-binding determinants on Ldb1.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1105898108

Localizing the NADP+ binding site on the MurB enzyme by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1105898108

LIM Domain Binding Proteins 1 and 2 Have Different Oligomeric States

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1105898108

Latent and active p53 are identical in conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1105898108

GATA zinc finger interactions modulate DNA binding and transactivation

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21844373

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12

1 reference

https://pubmed.ncbi.nlm.nih.gov/21844373

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1105898108

0 references

0 references

0 references