Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis (Q28265897)

Ernest Fraenkel

12

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Ross Hardison

Ross Hardison

8

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Mitchell J Weiss

Mitchell J Weiss

9

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Bradley Bernstein

11

Bradley E Bernstein

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author name string

Ming Yu

1

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Huafeng Xie

3

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Yocheved Schindler

4

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Tyler B Moran

5

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Yong Cheng

6

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Duonan Yu

7

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Stuart H Orkin

10

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Alan B Cantor

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

13

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language of work or name

English

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publication date

25 November 2009

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published in

Molecular Cell

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volume

36

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issue

4

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page(s)

682-95

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cites work

1 reference

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A global role for EKLF in definitive and primitive erythropoiesis

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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

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Global regulation of erythroid gene expression by transcription factor GATA-1

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Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1

20 March 2017

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X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

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Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1

20 March 2017

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A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction

20 March 2017

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Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis

20 March 2017

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An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes

20 March 2017

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Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor

20 March 2017

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Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

20 March 2017

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SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

20 March 2017

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The polycomb-group gene Ezh2 is required for early mouse development

7 April 2017

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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

7 April 2017

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Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

7 April 2017

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Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif.

7 April 2017

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Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development.

29 September 2017

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Congenital erythropoietic porphyria due to a mutation in GATA1: the first trans-acting mutation causative for a human porphyria

29 September 2017

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A hypothesis-based approach for identifying the binding specificity of regulatory proteins from chromatin immunoprecipitation data.

29 September 2017

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Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation

29 September 2017

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Developmental control via GATA factor interplay at chromatin domains

29 September 2017

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Use of protein biotinylation in vivo for chromatin immunoprecipitation

29 September 2017

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GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

29 September 2017

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GATA-1-mediated proliferation arrest during erythroid maturation.

29 September 2017

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Hematopoietic development: a balancing act.

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The N-terminal zinc finger of the erythroid transcription factor GATA-1 binds GATC motifs in DNA.

29 September 2017

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Metabolic biotinylation of recombinant proteins in mammalian cells and in mice

29 September 2017

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Consequences of GATA-1 deficiency in megakaryocytes and platelets

29 September 2017

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K-ras is an essential gene in the mouse with partial functional overlap with N-ras

29 September 2017

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29 September 2017

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29 September 2017

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The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

29 September 2017

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The human beta-globin gene 3' enhancer contains multiple binding sites for an erythroid-specific protein.

2 June 2018

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Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF.

2 June 2018

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Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system

27 November 2018

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GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression.

27 November 2018

1 reference

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Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene.

27 November 2018

1 reference

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Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells

27 November 2018

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The eed mutation disrupts anterior mesoderm production in mice

27 November 2018

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12 December 2020

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages

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12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

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12 December 2020

GATA zinc finger interactions modulate DNA binding and transactivation

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12 December 2020

10.1016/J.MOLCEL.2009.11.002

Identifiers

DOI

1 reference

248951

248951

1 reference

1 reference

1 reference