Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining (Q27675393)

1

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Shruti Malu

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Patricia Cortes

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Aneel K Aggarwal

Structural Insights into the Role of Domain Flexibility in Human DNA Ligase IV

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publication date

27 December 2012

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published in

Cell Reports

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volume

2

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issue

6

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page(s)

1505-12

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cites work

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Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

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Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions

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XLF regulates filament architecture of the XRCC4·ligase IV complex

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29 September 2017

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2 June 2018

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10.1016/J.CELREP.2012.11.004

27 November 2018

Identifiers

DOI

1 reference

3156529

3156529

1 reference

1 reference

1 reference