Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives (Q27675530)

From Wikidata

Jump to navigation Jump to search

scientific article

Structures of the human poly (ADP-ribose) glycohydrolase catalytic domain confirm catalytic mechanism and explain inhibition by ADP-HPD derivatives

Language	Label	Description	Also known as
English	Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives	scientific article	Structures of the human poly (ADP-ribose) glycohydrolase catalytic domain confirm catalytic mechanism and explain inhibition by ADP-HPD derivatives

Statements

scholarly article

0 references

Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives (English)

0 references

author name string

Julie A Tucker

1

0 references

Neil Bennett

2

0 references

Claire Brassington

3

0 references

Stephen T Durant

4

0 references

Giles Hassall

5

0 references

Geoff Holdgate

6

0 references

Mark McAlister

7

0 references

J Willem M Nissink

8

0 references

Caroline Truman

9

0 references

Martin Watson

10

0 references

language of work or name

0 references

publication date

2012

0 references

0 references

7

0 references

12

0 references

e50889

0 references

copyright license

Creative Commons Attribution 4.0 International

10 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

A magic triangle for experimental phasing of macromolecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Protein crystallization by surface entropy reduction: optimization of the SER strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

The macro domain is an ADP-ribose binding module

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

REFMAC5 for the refinement of macromolecular crystal structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Overview of the CCP4 suite and current developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Features and development of Coot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Experimental phasing with SHELXC/D/E: combining chain tracing with density modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Clustal W and Clustal X version 2.0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Automated structure solution with autoSHARP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

The Buccaneer software for automated model building. 1. Tracing protein chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Scaling and assessment of data quality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

The integration of macromolecular diffraction data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Methods used in the structure determination of bovine mitochondrial F1 ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Macromolecular TLS refinement in REFMAC at moderate resolutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

A graphical user interface to the CCP4 program suite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

The finer things in X-ray diffraction data collection

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

Data processing and analysis with the autoPROC toolbox

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

20 March 2017

An introduction to data reduction: space-group determination, scaling and intensity statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

7 April 2017

Single-strand break repair and genetic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

7 April 2017

Protein disorder prediction: implications for structural proteomics

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

7 April 2017

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Selective small molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Protein annotation and modelling servers at University College London

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

PARP and PARG inhibitors--new therapeutic targets in cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Poly(ADP-ribose) makes a date with death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Toward rational protein crystallization: A Web server for the design of crystallizable protein variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Entropy and surface engineering in protein crystallization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Caspase-3-mediated processing of poly(ADP-ribose) glycohydrolase during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Assignment of the poly(ADP-ribose) glycohydrolase gene (PARG) to human chromosome 10q11.23 and mouse chromosome 14B by in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

A13C NMR study of poly(adenosine diphosphate ribose) and its monomers: evidence of α-(1″→2′) ribofuranosyl ribofuranoside residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Structure of poly(adenosine diphosphate ribose): identification of 2'-[1''-ribosyl-2''-(or 3''-)(1'''-ribosyl)]adenosine-5',5'',5'''-tris(phosphate) as a branch linkage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

29 September 2017

Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

PrDOS: prediction of disordered protein regions from amino acid sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

Identification of three critical acidic residues of poly(ADP-ribose) glycohydrolase involved in catalysis: determining the PARG catalytic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

Poly(ADP-ribose) molecules formed during DNA repair in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

Purification and Properties of a Glycohydrolase from Calf Thymus Splitting Ribose-Ribose Linkages of Poly(Adenosine Diphosphate Ribose)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519477

2 June 2018

Radiation-induced mitotic catastrophe in PARG-deficient cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Isolation and cloning of rat poly(ADP-ribose) glycohydrolase: presence of a potential nuclear export signal conserved in mammalian orthologs.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

MNNG-induced cell death is controlled by interactions between PARP-1, poly(ADP-ribose) glycohydrolase, and XRCC1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Poly(etheno ADP-ribose) blocks poly(ADP-ribose) glycohydrolase activity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Identification of an Inhibitor Binding Site of Poly(ADP-ribose) Glycohydrolase

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Automated ligand placement and refinement with a combined force field and shape potential.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

[4] Combining constraints for electron-density modification

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050889

21 January 2018

Mode of action of poly(ADP-ribose) glycohydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoglycosidic cleavage of branched polymers by poly(ADP-ribose) glycohydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of poly(ADP-ribose)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PARG: a macrodomain in disguise

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23251397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0050889

0 references

2012PLoSO...750889T

0 references

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27675530&oldid=1951360202"