The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat (Q27676733)

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25 February 2020

title

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat (English)

1 reference

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25 February 2020

3

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25 February 2020

Katherine Bao

4

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25 February 2020

6

Nevan J Krogan

1 reference

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25 February 2020

author name string

Heather Upton

2

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25 February 2020

Seemay Chou

5

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25 February 2020

Qiang Zhou

7

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25 February 2020

Tom Alber

8

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25 February 2020

Ursula Schulze-Gahmen

1

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25 February 2020

language of work or name

English

0 references

publication date

5 March 2013

1 reference

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25 February 2020

2 references

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25 February 2020

volume

2

1 reference

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25 February 2020

page(s)

e00327

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Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

25 February 2020

cites work

1 reference

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Global landscape of HIV-human protein complexes

20 March 2017

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Crystal structure of HIV-1 Tat complexed with human P-TEFb

20 March 2017

1 reference

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A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription

20 March 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

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The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

20 March 2017

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Inference of macromolecular assemblies from crystalline state

20 March 2017

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20 March 2017

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Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

20 March 2017

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

20 March 2017

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

20 March 2017

1 reference

Crossref

https://api.crossref.org/works/10.7554/ELIFE.00327

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

22 April 2017

1 reference

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HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589825

Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.

29 September 2017

1 reference

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The super elongation complex (SEC) family in transcriptional control

29 September 2017

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The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output

29 September 2017

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The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription

29 September 2017

1 reference

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RNA polymerase II elongation control

29 September 2017

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The control of HIV transcription: keeping RNA polymerase II on track

29 September 2017

1 reference

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Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes

29 September 2017

1 reference

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Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin

29 September 2017

1 reference

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Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC).

29 September 2017

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Paused RNA polymerase II as a developmental checkpoint

29 September 2017

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HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP

29 September 2017

1 reference

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HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

29 September 2017

1 reference

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AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

29 September 2017

1 reference

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The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling

29 September 2017

1 reference

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The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation

29 September 2017

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HIV-1 tat transcriptional activity is regulated by acetylation

29 September 2017

1 reference

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Suite of three protein crystallography beamlines with single superconducting bend magnet as the source.

2 June 2018

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DoGSiteScorer: a web server for automatic binding site prediction, analysis and druggability assessment.

21 January 2018

1 reference

Crossref

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21 January 2018

Identifiers

DOI

10.7554/ELIFE.00327

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

894870

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OpenCitations bibliographic resource ID

25 February 2020

894870

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

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25 February 2020

1 reference