Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes (Q27676742)

23 June 2017

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes (English)

1 reference

23 June 2017

0 references

18

1 reference

23 June 2017

Stephanie Gras

5

0 references

David K. Cole

David K Cole

2

0 references

Andrew K Sewell

Andrew K Sewell

21

0 references

John Miles

8

John J Miles

1 reference

23 June 2017

Mark Peakman

19

0 references

Emma Gostick

9

Emma Gostick

1 reference

23 June 2017

Anna Fuller

7

1 reference

ORCID Public Data File 2021

Jan W Drijfhout

11

Jan W Drijfhout

1 reference

23 June 2017

Anna M Bulek

1

1 reference

23 June 2017

Ania Skowera

3

1 reference

23 June 2017

Garry Dolton

4

1 reference

23 June 2017

Florian Madura

6

1 reference

23 June 2017

David A Price

10

1 reference

23 June 2017

Robin R Knight

12

1 reference

23 June 2017

Guo C Huang

13

1 reference

23 June 2017

Nikolai Lissin

14

1 reference

23 June 2017

Peter E Molloy

15

1 reference

23 June 2017

Linda Wooldridge

16

1 reference

23 June 2017

Bent K Jakobsen

17

1 reference

23 June 2017

Pierre J Rizkallah

20

1 reference

23 June 2017

language of work or name

English

0 references

publication date

15 January 2012

1 reference

23 June 2017

1 reference

23 June 2017

13

1 reference

23 June 2017

283-289

1 reference

23 June 2017

3

1 reference

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

23 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

How a single T cell receptor recognizes both self and foreign MHC

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

The molecular basis of TCR germline bias for MHC is surprisingly simple

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

How TCRs bind MHCs, peptides, and coreceptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

A single autoimmune T cell receptor recognizes more than a million different peptides

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

T cell receptor recognition of self and foreign antigens in the induction of autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Antigen recognition by CD1d-restricted NKT T cell receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Analysis of islet inflammation in human type 1 diabetes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

AMoRe: classical and modern.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Human TCR-binding affinity is governed by MHC class restriction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378510

T cell tolerance by clonal elimination in the thymus

2 June 2018

1 reference

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

21 January 2018

1 reference

The development of new density gradient media for purifying human islets and islet-quality assessments

21 January 2018

1 reference

Stable, soluble T-cell receptor molecules for crystallization and therapeutics

21 January 2018

1 reference

T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding

21 January 2018

1 reference

Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22245737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aberrant expression of class II major histocompatibility complex molecules by B cells and hyperexpression of class I major histocompatibility complex molecules by insulin containing islets in type 1 (insulin-dependent) diabetes mellitus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22245737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

xia2: an expert system for macromolecular crystallography data reduction

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI.2206

1 reference

OpenCitations bibliographic resource ID

23 June 2017

1618319

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference