The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice (Q36079920)

12 August 2017

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title

The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice (English)

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12 August 2017

Teresa P DiLorenzo

1

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12 August 2017

David V Serreze

series ordinal

2

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12 August 2017

language of work or name

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1 April 2005

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12 August 2017

published in

Immunological Reviews

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12 August 2017

volume

204

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12 August 2017

page(s)

250-263

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Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

12 August 2017

cites work

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Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

21 January 2018

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21 January 2018

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The HLA class I A locus affects susceptibility to type 1 diabetes

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Beta cell MHC class I is a late requirement for diabetes

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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

21 January 2018

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A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes

21 January 2018

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Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

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RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes

21 January 2018

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Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

21 January 2018

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B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice

21 January 2018

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B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

21 January 2018

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CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

21 January 2018

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Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

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Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus

21 January 2018

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Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase

21 January 2018

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During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities

21 January 2018

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Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.

21 January 2018

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Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain

21 January 2018

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Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice

21 January 2018

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MHC characterization of ALR and ALS mice: respective similarities to the NOD and NON strains

21 January 2018

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Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice

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A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

21 January 2018

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21 January 2018

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Dissociation of peripheral T cell responses from thymocyte negative selection by weak agonists supports a spare receptor model of T cell activation

21 January 2018

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Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

21 January 2018

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In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes

21 January 2018

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Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

21 January 2018

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21 January 2018

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Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells

21 January 2018

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Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

21 January 2018

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Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigens

21 January 2018

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alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

21 January 2018

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A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

21 January 2018

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Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

21 January 2018

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Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

21 January 2018

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A blast from the past: clearance of apoptotic cells regulates immune responses.

21 January 2018

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Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

21 January 2018

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Apoptosis, subcellular particles, and autoimmunity.

21 January 2018

1 reference

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Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Tissue targeting of T cells by DCs and microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00244.X

10.1111/J.0105-2896.2005.00244.X

21 January 2018

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DOI

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release_vbchjwmntrashiyxkadoxq4tlm

12 August 2017

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