Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α (Q27677013)

2

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Alex A Parent

3

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Valerie Cavett

4

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Jason Nowak

5

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Travis S Hughes

6

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Douglas J Kojetin

7

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John A Katzenellenbogen

8

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Kendall W Nettles

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases

9

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publication date

May 2013

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published in

Nature Chemical Biology

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volume

9

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issue

5

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page(s)

326-32

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cites work

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20 March 2017

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20 March 2017

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Interaction of estrogen receptor alpha with 3-methyladenine DNA glycosylase modulates transcription and DNA repair

20 March 2017

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Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ

20 March 2017

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

7 April 2017

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7 April 2017

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Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism.

29 September 2017

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29 September 2017

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Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor

29 September 2017

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29 September 2017

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Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12.

29 September 2017

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A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer

29 September 2017

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Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity

29 September 2017

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29 September 2017

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GREB 1 is a critical regulator of hormone dependent breast cancer growth

29 September 2017

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29 September 2017

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Ligand control of coregulator recruitment to nuclear receptors

29 September 2017

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29 September 2017

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29 September 2017

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Full-length estrogen receptor α and its ligand-binding domain adopt different conformations upon binding ligand

29 September 2017

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29 September 2017

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AIB1 enhances estrogen-dependent induction of cyclin D1 expression

29 September 2017

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Structures of Src-family tyrosine kinases

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631275

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631275

Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers

29 September 2017

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Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631275

Direct detection of structurally resolved dynamics in a multiconformation receptor-ligand complex

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631275

Estrogen response elements alter coactivator recruitment through allosteric modulation of estrogen receptor beta conformation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631275

Ivano Bertini: 1940-2012.

2 June 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1214

Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23524984

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1214

1 reference

Dimensions Publication ID

2140784

1023394103

0 references

2140784

1 reference

1 reference

1 reference