Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 (Q27678306)

alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-Gly

74885

1 reference

alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-Gly

74888

1 reference

N-{alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc}-DHPE

74891

1 reference

N-{alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc}-DHPE

74893

1 reference

N-{alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc}-AOPE

74912

1 reference

1 reference

5

0 references

Jeong Hyun Lee

Jeong Hyun Lee

2

0 references

Katie Doores

Katie J Doores

3

0 references

Marc C. Deller

Marc C Deller

17

0 references

Ten Feizi

Ten Feizi

20

0 references

Ian Andrew Wilson

27

Ian A Wilson

0 references

Dennis R. Burton

25

Dennis R Burton

0 references

Andrew B Ward

26

Andrew B Ward

0 references

Rogier W Sanders

21

Rogier W Sanders

0 references

John P. Moore

23

John P Moore

0 references

Henry Tien

19

Henry Tien

0 references

Leopold Kong

1

Leopold Kong

0 references

Robyn L Stanfield

24

Robyn L Stanfield

0 references

Albert Cupo

9

Albert Cupo

0 references

Per Johan Klasse

10

Per-Johan Klasse

0 references

Yuanzi Hua

14

Yuanzi Hua

0 references

Reza Khayat

16

Reza Khayat

0 references

Andre J Marozsan

8

Andre Marozsan

0 references

C King

13

C Richter King

0 references

author name string

Charles D Murin

4

0 references

Ryan McBride

6

0 references

Yan Liu

7

0 references

Simon Hoffenberg

11

0 references

Michael Caulfield

12

0 references

Khoa M Le

15

0 references

Thomas Clayton

18

0 references

James C Paulson

Nature Structural & Molecular Biology

22

0 references

publication date

July 2013

0 references

published in

0 references

volume

20

0 references

page(s)

796-803

0 references

issue

7

0 references

cites work

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

20 March 2017

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Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

20 March 2017

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

20 March 2017

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Molecular architecture of native HIV-1 gp120 trimers

20 March 2017

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

20 March 2017

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

20 March 2017

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EMAN: semiautomated software for high-resolution single-particle reconstructions

20 March 2017

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A new generation of the IMAGIC image processing system

20 March 2017

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Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin

20 March 2017

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Structural basis of lectin-carbohydrate recognition

20 March 2017

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

20 March 2017

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Antibody neutralization and escape by HIV-1

7 April 2017

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Broad neutralization coverage of HIV by multiple highly potent antibodies

7 April 2017

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Appion: an integrated, database-driven pipeline to facilitate EM image processing

7 April 2017

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

7 April 2017

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

7 April 2017

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Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes

7 April 2017

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Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.

29 September 2017

1 reference

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Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

29 September 2017

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Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

29 September 2017

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HIV-1 virus-like particles bearing pure env trimers expose neutralizing epitopes but occlude nonneutralizing epitopes

29 September 2017

1 reference

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Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

29 September 2017

1 reference

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The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

29 September 2017

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Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant

29 September 2017

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A clustering approach to multireference alignment of single-particle projections in electron microscopy

29 September 2017

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Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization

29 September 2017

1 reference

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Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

29 September 2017

1 reference

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DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

29 September 2017

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Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization

29 September 2017

1 reference

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SPARX, a new environment for Cryo-EM image processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

29 September 2017

1 reference

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Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

A model for neutralization of viruses based on antibody coating of the virion surface

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

Regulation of N-linked core glycosylation: use of a site-directed mutagenesis approach to identify Asn-Xaa-Ser/Thr sequons that are poor oligosaccharide acceptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

Glycosylation: heterogeneity and the 3D structure of proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823233

Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2594

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2594

21 January 2018

Identifiers

DOI

10.1038/NSMB.2594

1 reference

Dimensions Publication ID

190579

1021044608

0 references

190579

1 reference

1 reference

1 reference