On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs (Q27679956)

1

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13 June 2020

Nei-Li Chan

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13 June 2020

author name string

Yi-Ching Li

2

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13 June 2020

Ying-Ren Wang

3

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13 June 2020

Tsai-Kun Li

4

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13 June 2020

language of work or name

English

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publication date

December 2013

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published in

Nucleic Acids Research

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13 June 2020

volume

41

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13 June 2020

issue

22

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13 June 2020

page(s)

10630-10640

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Creative Commons Attribution 3.0 Unported

13 June 2020

copyright license

start time

10 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage

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Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide

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Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)

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Targeting DNA topoisomerase II in cancer chemotherapy

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Structural basis for gate-DNA recognition and bending by type IIA topoisomerases

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Cellular roles of dna topoisomerases: a molecular perspective

20 March 2017

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Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin

20 March 2017

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

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Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

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New mechanistic and functional insights into DNA topoisomerases.

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Identification of the molecular basis of doxorubicin-induced cardiotoxicity

29 September 2017

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Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity

29 September 2017

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Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions

29 September 2017

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All tangled up: how cells direct, manage and exploit topoisomerase function

29 September 2017

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The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

29 September 2017

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DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

29 September 2017

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DNA topoisomerase II, genotoxicity, and cancer

29 September 2017

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29 September 2017

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Toxicity of the topoisomerase II inhibitors

29 September 2017

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Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide

29 September 2017

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29 September 2017

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29 September 2017

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Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives

29 September 2017

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DNA topoisomerase poisons as antitumor drugs

29 September 2017

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Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin.

29 September 2017

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29 September 2017

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Comparative study of doxorubicin, mitoxantrone, and epirubicin in combination with ICRF-187 (ADR-529) in a chronic cardiotoxicity animal model

27 November 2018

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12 December 2020

Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane

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12 December 2020

Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Interactions of antitumor agents ametantrone∗∗Trade name for the salt of 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione (Fig. 1, I). Abbreviations: HAQ, ANT; NSC-287513. and mitoxantrone (novatrone)††Trade name for the sa

1 reference

12 December 2020

Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKT828

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24038465%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24038465%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

24038465

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24038465%20AND%20SRC:MED&resulttype=core&format=json