T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions (Q27680546)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24196962%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Andrew Godkin

6

1 reference

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5 June 2020

Andrew K Sewell

16

1 reference

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5 June 2020

Anna Fuller

8

1 reference

ORCID Public Data File 2021

author name string

Kim M Miles

2

1 reference

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5 June 2020

Florian Madura

3

1 reference

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5 June 2020

Christopher J Holland

4

1 reference

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5 June 2020

Andrea J A Schauenburg

5

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5 June 2020

Anna M Bulek

7

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5 June 2020

Hephzibah J E Akpovwa

9

1 reference

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5 June 2020

Phillip G Pymm

10

1 reference

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5 June 2020

Nathaniel Liddy

11

1 reference

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5 June 2020

Malkit Sami

12

1 reference

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5 June 2020

Yi Li

13

1 reference

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5 June 2020

Pierre J Rizkallah

14

1 reference

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5 June 2020

Bent K Jakobsen

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24196962%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 June 2020

language of work or name

English

0 references

publication date

10 January 2014

0 references

published in

1 reference

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5 June 2020

volume

289

1 reference

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5 June 2020

issue

2

1 reference

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5 June 2020

page(s)

628-638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24196962%20AND%20SRC:MED&resulttype=core&format=json

Increased peptide contacts govern high affinity binding of a modified TCR whilst maintaining a native pMHC docking mode

5 June 2020

cites work

1 reference

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T-cell Receptor Specificity Maintained by Altered Thermodynamics

20 March 2017

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Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers

20 March 2017

1 reference

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Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

20 March 2017

1 reference

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A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

20 March 2017

1 reference

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Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

20 March 2017

1 reference

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Allelic polymorphism in the T cell receptor and its impact on immune responses

20 March 2017

1 reference

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Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

20 March 2017

1 reference

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T cell allorecognition via molecular mimicry

20 March 2017

1 reference

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Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

20 March 2017

1 reference

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Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

20 March 2017

1 reference

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Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

20 March 2017

1 reference

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Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry

20 March 2017

1 reference

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How a single T cell receptor recognizes both self and foreign MHC

20 March 2017

1 reference

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A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

20 March 2017

1 reference

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Crystal structure of a T cell receptor bound to an allogeneic MHC molecule

20 March 2017

1 reference

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

20 March 2017

1 reference

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

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20 March 2017

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Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection

20 March 2017

1 reference

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The molecular basis of TCR germline bias for MHC is surprisingly simple

20 March 2017

1 reference

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Reversal of the TCR stop signal by CTLA-4

20 March 2017

1 reference

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

20 March 2017

1 reference

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How TCRs bind MHCs, peptides, and coreceptors

20 March 2017

1 reference

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T-cell antigen receptor genes and T-cell recognition

7 April 2017

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The basis for limited specificity and MHC restriction in a T cell receptor interface

7 April 2017

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The T-cell receptor is not hardwired to engage MHC ligands

29 September 2017

1 reference

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A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned

29 September 2017

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A single autoimmune T cell receptor recognizes more than a million different peptides

29 September 2017

1 reference

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Structural and biophysical determinants of αβ T-cell antigen recognition

29 September 2017

1 reference

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High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics.

29 September 2017

1 reference

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The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor

29 September 2017

1 reference

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Human TCR-binding affinity is governed by MHC class restriction

29 September 2017

1 reference

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The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy.

29 September 2017

1 reference

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The kinetic-segregation model: TCR triggering and beyond

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

Structural and kinetic basis for heightened immunogenicity of T cell vaccines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

What do TCR-pMHC crystal structures teach us about MHC restriction and alloreactivity?

29 September 2017

1 reference

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Molecular interactions mediating T cell antigen recognition

29 September 2017

1 reference

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Emerging principles for T cell receptor recognition of antigen in cellular immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

29 September 2017

1 reference

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T-cell-receptor affinity and thymocyte positive selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3887192

Polarity of T cell shape, motility, and sensitivity to antigen

29 September 2017

1 reference

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Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

29 September 2017

1 reference

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Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

2 June 2018

1 reference

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Why must T cells be cross-reactive?

2 June 2018

1 reference

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Directed evolution of human T-cell receptors with picomolar affinities by phage display.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

Stable, soluble T-cell receptor molecules for crystallization and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

Crystal structure of HLA-A*2402 complexed with a telomerase peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

Analyzing a kinetic titration series using affinity biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

Rfreeand theRfreeratio. II. Calculation of the expected values and variances of cross-validation statistics in macromolecular least-squares refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.522110

A very high level of crossreactivity is an essential feature of the T-cell receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24196962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24196962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.522110

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24196962%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24196962%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

2 references