Agonist-bound structure of the human P2Y12 receptor (Q27683598)

14

0 references

Vadim Cherezov

13

0 references

Kaihua Zhang

Kaihua Zhang

2

0 references

Raymond C. Stevens

Raymond C Stevens

16

0 references

Christa E Müller

Christa E Müller

10

0 references

Kenneth A. Jacobson

Kenneth A Jacobson

15

0 references

Zhan-Guo Gao

3

Zhan-Guo Gao

0 references

Silvia Paoletta

4

Silvia Paoletta

0 references

Gye Won Han

6

Gye Won Han

0 references

Jiang Hualiang

12

Hualiang Jiang

0 references

author name string

Jin Zhang

1

0 references

Dandan Zhang

5

0 references

Tingting Li

7

0 references

Limin Ma

8

0 references

Wenru Zhang

9

0 references

Huaiyu Yang

11

0 references

Beili Wu

17

0 references

Qiang Zhao

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

18

0 references

language of work or name

English

0 references

publication date

1 May 2014

0 references

published in

Nature

0 references

volume

509

0 references

issue

7498

0 references

page(s)

119-22

0 references

cites work

1 reference

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Activation and allosteric modulation of a muscarinic acetylcholine receptor

20 March 2017

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High-resolution crystal structure of human protease-activated receptor 1

20 March 2017

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Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

20 March 2017

1 reference

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Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

20 March 2017

1 reference

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

20 March 2017

1 reference

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Structure of an agonist-bound human A2A adenosine receptor

20 March 2017

1 reference

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

20 March 2017

1 reference

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Structure and function of an irreversible agonist-β(2) adrenoceptor complex

20 March 2017

1 reference

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

20 March 2017

1 reference

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Crystal structure of opsin in its G-protein-interacting conformation

20 March 2017

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

20 March 2017

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

20 March 2017

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

20 March 2017

1 reference

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20 March 2017

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Phasercrystallographic software

20 March 2017

1 reference

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REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

20 March 2017

1 reference

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

20 March 2017

1 reference

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Crystallizing membrane proteins using lipidic mesophases

7 April 2017

1 reference

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Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12.

7 April 2017

1 reference

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Subtleties in GPCR drug discovery: a medicinal chemistry perspective

29 September 2017

1 reference

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Ice breaking in GPCR structural biology

29 September 2017

1 reference

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Structure and activation of rhodopsin

29 September 2017

1 reference

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The platelet P2Y₁₂ receptor for adenosine diphosphate: congenital and drug-induced defects.

29 September 2017

1 reference

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Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.

29 September 2017

1 reference

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The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4128917

Involvement of basic amino acid residues in transmembrane regions 6 and 7 in agonist and antagonist recognition of the human platelet P2Y(12)-receptor

29 September 2017

1 reference

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Identification of a potent inverse agonist at a constitutively active mutant of human P2Y12 receptor

29 September 2017

1 reference

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Adenine triphosphate nucleotides are antagonists at the P2Y receptor.

29 September 2017

1 reference

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Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation.

29 September 2017

1 reference

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Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13288

Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13288

Identification and characterization of a novel P2Y 12 variant in a patient diagnosed with type 1 von Willebrand disease in the European MCMDM-1VWD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13288

The 73-kDa heat shock cognate protein is a CXCR4 binding protein that regulates the receptor endocytosis and the receptor-mediated chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13288

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13288

21 January 2018

Identifiers

DOI

10.1038/NATURE13288

1 reference

Dimensions Publication ID

1029449748

0 references

1 reference

1 reference

PubMed publication ID

24784220

1 reference