A potential link between phosphate and aging--lessons from Klotho-deficient mice (Q27687316)

Crossref

publication date

April 2010

1 reference

Mechanisms of Ageing and Development

published in

1 reference

volume

131

1 reference

issue

4

1 reference

page(s)

270-5

1 reference

Phenotype and course of Hutchinson-Gilford progeria syndrome

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Klotho converts canonical FGF receptor into a specific receptor for FGF23

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Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase

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Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism

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29 September 2017

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A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

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Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D.

29 September 2017

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Dietary P(i) deprivation in rats affects liver cAMP, glycogen, key steps of gluconeogenesis and glucose production

2 June 2018

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Up-regulation of liver glucose-6-phosphatase in rats fed with a P(i)-deficient diet

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2 June 2018

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2 June 2018

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19 June 2018

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27 November 2018

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Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice.

27 November 2018

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27 November 2018

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27 November 2018

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Relation between serum phosphate level and cardiovascular event rate in people with coronary disease

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Klotho insufficiency causes decrease of ribosomal RNA gene transcription activity, cytoplasmic RNA and rough ER in the spinal anterior horn cells.

27 November 2018

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FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

27 November 2018

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27 November 2018

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27 November 2018

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Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress.

27 November 2018

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Expression of Klotho protein in the inner ear.

27 November 2018

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Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.

27 November 2018

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Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene

27 November 2018

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Severely reduced production of klotho in human chronic renal failure kidney.

27 November 2018

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Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life.

27 November 2018

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Effect of calorie restriction on in vivo glucose metabolism by individual tissues in rats.

27 November 2018

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Vesicular and ulcerative dermatopathy resembling superficial necrolytic dermatitis in captive black rhinoceroses (Diceros bicornis).

27 November 2018

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Relation between phosphate metabolites and oxygen consumption of heart in vivo

27 November 2018

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12 December 2020

Controlling the epidemic of cardiovascular disease in chronic renal disease: report from the National Kidney Foundation Task Force on cardiovascular disease

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Intracellular pH and inorganic phosphate content of heart in vivo: a 31P-NMR study

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Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice

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12 December 2020

Hutchinson-Gilford progeria syndrome

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Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients

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Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice

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The Snell dwarf mutation Pit1(dw) can increase life span in mice

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Comparison of serum and plasma for determination of blood biochemical values in Malaysian flying foxes (Pteropus vampyrus)

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Serum biochemistry and hematology values and hemoglobin electrophoresis in Persian squirrels (Sciurus anomalus)

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Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis

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Dietary restriction-induced life extension: a broadly based biological phenomenon

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The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc

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10.1016/J.MAD.2010.02.008

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

20197072

1 reference