Structural aspects and physiological consequences of APP/APLP trans-dimerization (Q27687528)

1

1 reference

Katja Wagner

2

1 reference

Simone Eggert

3

1 reference

Stefan Kins

5

1 reference

publication date

April 2012

1 reference

Experimental Brain Research

1 April 2012

3 references

15 December 2019

19 December 2019

21 December 2019

4 references

15 December 2019

19 December 2019

21 December 2019

217

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issue

3-4

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page(s)

389-95

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The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization

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1 reference

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Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP

20 March 2017

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Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein

20 March 2017

1 reference

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Interaction of reelin with amyloid precursor protein promotes neurite outgrowth

20 March 2017

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Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2

20 March 2017

1 reference

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The amyloid-beta precursor protein: integrating structure with biological function

20 March 2017

1 reference

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Homo- and heterodimerization of APP family members promotes intercellular adhesion

20 March 2017

1 reference

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Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage

20 March 2017

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Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

20 March 2017

1 reference

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The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

20 March 2017

2 references

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20 March 2017

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Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

21 January 2018

1 reference

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Mints as adaptors. Direct binding to neurexins and recruitment of munc18

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

20 March 2017

1 reference

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Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

20 March 2017

1 reference

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Neuroligins and neurexins: linking cell adhesion, synapse formation and cognitive function

20 March 2017

1 reference

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The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Isoform-specific knockout of FE65 leads to impaired learning and memory

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Notch signalling: a simple pathway becomes complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Alzheimer's disease is a synaptic failure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Amyloid precursor protein trafficking, processing, and function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

APP physiological and pathophysiological functions: insights from animal models.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

AICD nuclear signaling and its possible contribution to Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Biology and pathophysiology of the amyloid precursor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Induced dimerization of the amyloid precursor protein leads to decreased amyloid-beta protein production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral thrombosis

29 September 2017

1 reference

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Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

29 September 2017

1 reference

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Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The FE65 proteins and Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The APP family of proteins: similarities and differences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Cell adhesion molecules: signalling functions at the synapse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Basal lamina and the organization of neuromuscular synapses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Post-translational processing and turnover kinetics of presynaptically targeted amyloid precursor superfamily proteins in the central nervous system.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

APP gene family. Alternative splicing generates functionally related isoforms.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein li

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308009

Solution Conformation and Heparin-induced Dimerization of the Full-length Extracellular Domain of the Human Amyloid Precursor Protein

2 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2878-6

The effects of amyloid precursor protein on postsynaptic composition and activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2878-6

Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2878-6

Fyn-Tau-Amyloid: A Toxic Triad

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21952790

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00221-011-2878-6

0 references

Dimensions Publication ID

1006304073

0 references

Fatcat ID

release_3gustfg3iva2fj4acxo74g3uyi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3gustfg3iva2fj4acxo74g3uyi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

PubMed publication ID

21952790

1 reference