Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns (Q27694684)

publication date

April 2010

1 reference

1 reference

11

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issue

4

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page(s)

270-8

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Complex landscapes of somatic rearrangement in human breast cancer genomes

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DNA end resection: many nucleases make light work

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Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint

20 March 2017

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Homologous recombination in DNA repair and DNA damage tolerance

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Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication

20 March 2017

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The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

20 March 2017

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Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

20 March 2017

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Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

20 March 2017

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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

20 March 2017

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Regulation and mechanisms of mammalian double-strand break repair

20 March 2017

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Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins

20 March 2017

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DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination

20 March 2017

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Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

20 March 2017

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Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins

20 March 2017

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

20 March 2017

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A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.

20 March 2017

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Break-induced replication and telomerase-independent telomere maintenance require Pol32.

20 March 2017

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Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

20 March 2017

1 reference

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GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

A screen for genes required for meiosis and spore formation based on whole-genome expression.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Break-induced replication and recombinational telomere elongation in yeast

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

ATR activation and replication fork restart are defective in FANCM-deficient cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Genomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

A microhomology-mediated break-induced replication model for the origin of human copy number variation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Genome-wide studies highlight indirect links between human replication origins and gene regulation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Break-induced replication: what is it and what is it for?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Plx1 is required for chromosomal DNA replication under stressful conditions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Differential usage of non-homologous end-joining and homologous recombination in double strand break repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

The DNA damage response during DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Identification and functional analysis of TopBP1 and its homologs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

DNA replication origins in the Schizosaccharomyces pombe genome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

The Mre11 nuclease is not required for 5' to 3' resection at multiple HO-induced double-strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

A coordinated temporal interplay of nucleosome reorganization factor, sister chromatin cohesion factor, and DNA polymerase alpha facilitates DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

DSB repair: the yeast paradigm

29 September 2017

1 reference

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ATR and ATM regulate the timing of DNA replication origin firing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Genome-wide distribution of DNA replication origins at A+T-rich islands in Schizosaccharomyces pombe

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Mechanism and regulation of human non-homologous DNA end-joining

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Rad54, a Jack of all trades in homologous recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogaster

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Stepwise assembly of initiation complexes at budding yeast replication origins during the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

In vivo protein-DNA interactions at human DNA replication origin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Analysis of chromosomal replicons in early embryos of Drosophila melanogaster by two-dimensional gel electrophoresis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Regulation of replicon size in Xenopus egg extracts.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854594

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

MCM9 binds Cdt1 and is required for the assembly of prereplication complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

MCM8 is an MCM2-7-related protein that functions as a DNA helicase during replication elongation and not initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Getting connected: analysis and principles of biological networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

Template switching during break-induced replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2010.27

DNA end-joining: from yeast to man

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20203697

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The many interfaces of Mre11

1 reference

https://pubmed.ncbi.nlm.nih.gov/20203697

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transition in specification of embryonic metazoan DNA replication origins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20203697

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOR.2010.27

0 references

1 reference

PubMed publication ID

20203697

1 reference